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Biological Determinants of ILC Reactivity for Immune Responses in Health and Disease


Local and systemic features of ILC immunometabolism

Author(s): Laura Surace; James P. Di Santo
Published in: Current Opinion in Hematology, 2022, ISSN 1065-6251
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/moh.0000000000000722

Defects in mucosal immunity and nasopharyngeal dysbiosis in HSC transplanted SCID patients with IL2RG/JAK3 deficiency

Author(s): Goncalves, Pedro; Doisne, Jean-Marc; Eri, Toshiki; Charbit, Bruno; Bondet, Vincent; Posseme, Celine; Llibre, Alba; The Milieu Interieur , Consortium; Casrouge, Armanda; Lenoir, Christelle; Neven, Bénédicte; Duffy, Darragh; Fischer, Alain; Di Santo, James
Published in: Blood, Issue 3, 2022, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood.2021014654

Inflammation triggers ILC3 patrolling of the intestinal barrier

Author(s): Jarade A, Garcia Z, Marie S, Demera A, Prinz I, Bousso P, Di Santo JP, Serafini N.
Published in: Nature Immunology, Issue 15292908, 2022, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-022-01284-1

Dichotomous metabolic networks govern human ILC2 proliferation and function.

Author(s): Laura Surace; Jean-Marc Doisne; Carys A. Croft; Carys A. Croft; Anna Thaller; Anna Thaller; Pedro Escoll; Solenne Marie; Natalia Petrosemoli; Vincent Guillemot; Valerie Dardalhon; Davide Topazio; Antonia Cama; Carmen Buchrieser; Naomi Taylor; Ido Amit; Olimpia Musumeci; James P. Di Santo
Published in: Nature Immunology, Issue 9, 2021, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-021-01043-8

Polarized mitochondria as guardians of NK cell fitness

Author(s): Laura Surace, Jean-Marc Doisne, Pedro Escoll, Solenne Marie, Valerie Dardalhon, Carys Croft, Anna Thaller, Davide Topazio, Angelo Sparaneo, Antonia Cama, Olimpia Musumeci, Aurelio d’Ecclesia, Carmen Buchrieser, Naomi Taylor, James P. Di Santo
Published in: Blood Advances, Issue 5/1, 2021, Page(s) 26-38, ISSN 2473-9529
Publisher: American Society of Hematology
DOI: 10.1182/bloodadvances.2020003458

Microbiota stimulation generates LCMV-specific memory CD8+ T cells in SPF mice and determines their TCR repertoire during LCMV infection.

Author(s): Pedro Gonçalves; Pedro Gonçalves; Sary El Daker; Florence Vasseur; Nicolas Serafini; Nicolas Serafini; Annick Lim; Orly Azogui; Hélène Decaluwe; Delphine Guy-Grand; Delphine Guy-Grand; Antonio A. Freitas; James P. Di Santo; James P. Di Santo; Benedita Rocha; Benedita Rocha
Published in: "Molecular Immunology, Elsevier, 2020, 124, pp.125 - 141. ⟨10.1016/j.molimm.2020.05.012⟩", Issue 4, 2020, ISSN 0161-5890
Publisher: Pergamon Press
DOI: 10.1016/j.molimm.2020.05.012

Antibody-coated microbiota in nasopharynx of healthy individuals and IVIg-treated patients with hypogammaglobulinemia.

Author(s): Pedro Gonçalves; Pedro Gonçalves; Bruno Charbit; Christelle Lenoir; Darragh Duffy; Darragh Duffy; Alain Fischer; James P. Di Santo; James P. Di Santo
Published in: Journal of allergy and clinical immunology, Issue 4, 2020, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2020.01.002

Group 3 innate lymphoid cells mediate host defense against attaching and effacing pathogens.

Author(s): Angélique Jarade; James P. Di Santo; Nicolas Serafini
Published in: Current Opinion in Microbiology, Issue 2, 2021, ISSN 1369-5274
Publisher: Elsevier BV
DOI: 10.1016/j.mib.2021.06.005

Intrathymic Deletion of IL-7 Reveals a Contribution of the Bone Marrow to Thymic Rebound Induced by Androgen Blockade

Author(s): Pedro M. Rodrigues, Ana R. Ribeiro, Nicolas Serafini, Catarina Meireles, James P. Di Santo, Nuno L. Alves
Published in: The Journal of Immunology, Issue 200/4, 2018, Page(s) 1389-1398, ISSN 0022-1767
Publisher: American Association of Immunologists
DOI: 10.4049/jimmunol.1701112

A Cross-Talk Between Microbiota-Derived Short-Chain Fatty Acids and the Host Mucosal Immune System Regulates Intestinal Homeostasis and Inflammatory Bowel Disease

Author(s): Pedro Gonçalves, João Ricardo Araújo, James P Di Santo
Published in: Inflammatory Bowel Diseases, Issue 24/3, 2018, Page(s) 558-572, ISSN 1078-0998
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1093/ibd/izx029

Innate Lymphoid Cell Development: A T Cell Perspective

Author(s): Dylan E. Cherrier, Nicolas Serafini, James P. Di Santo
Published in: Immunity, Issue 48/6, 2018, Page(s) 1091-1103, ISSN 1074-7613
Publisher: Cell Press
DOI: 10.1016/j.immuni.2018.05.010

Innate Lymphoid Cells: 10 Years On

Author(s): Eric Vivier, David Artis, Marco Colonna, Andreas Diefenbach, James P. Di Santo, Gérard Eberl, Shigeo Koyasu, Richard M. Locksley, Andrew N.J. McKenzie, Reina E. Mebius, Fiona Powrie, Hergen Spits
Published in: Cell, Issue 174/5, 2018, Page(s) 1054-1066, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2018.07.017

ILC-poiesis: Ensuring tissue ILC differentiation at the right place and time

Author(s): Ai Ing Lim, James P. Di Santo
Published in: European Journal of Immunology, Issue 49/1, 2018, Page(s) 11-18, ISSN 0014-2980
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201747294

An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials

Author(s): Wei Xu, Dylan E. Cherrier, Sylvestre Chea, Christian Vosshenrich, Nicolas Serafini, Maxime Petit, Pentao Liu, Rachel Golub, James P. Di Santo
Published in: Immunity, 2019, ISSN 1074-7613
Publisher: Cell Press
DOI: 10.1016/j.immuni.2019.02.022

Trained ILC3 responses promote intestinal defense

Author(s): Nicolas Serafini; Angélique Jarade; Laura Surace; Pedro Goncalves; Odile Sismeiro; Hugo Varet; Rachel Legendre; Jean-Yves Coppee; Olivier Disson; Scott K. Durum; Gad Frankel; James P. Di Santo
Published in: Science, Issue 2, 2022, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aaz8777

Notch, RORC and IL-23 signals cooperate to promote multi-lineage human innate lymphoid cell differentiation

Author(s): Carys A. Croft, Anna Thaller, Solenne Marie, Jean-Marc Doisne, Laura Surace, Rui Yang, Anne Puel, Jacinta Bustamante, Jean-Laurent Casanova, James P. Di Santo
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-32089-3

The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses

Author(s): Cedric N. Berger, Valerie F. Crepin, Theodoros I. Roumeliotis, James C. Wright, Nicolas Serafini, Meirav Pevsner-Fischer, Lu Yu, Eran Elinav, James P. Di Santo, Jyoti S. Choudhary, Gad Frankel
Published in: PLOS Pathogens, Issue 14/10, 2018, Page(s) e1007406, ISSN 1553-7374
Publisher: PLOS
DOI: 10.1371/journal.ppat.1007406

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