Molecular organization and dynamics of synapse diversity: novel genetic, imaging and computational approaches

Project Information

SYNNOVATE

Grant agreement ID: 695568

DOI

10.3030/695568

Project closed

EC signature date 11 July 2016

Start date 1 August 2016

End date 31 July 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

THE UNIVERSITY OF EDINBURGH
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex

Author(s): Katie Morris, Edita Bulovaite, Takeshi Kaizuka, Sebastian Schnorrenberg, Candace Adams, Noboru H Komiyama, Lorena Mendive-Tapia, Seth GN Grant, Mathew H Horrocks
Published in: eLife, Issue 13, 2024, Page(s) RP99303, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.99303.1

Architecture of the Mouse Brain Synaptome

Author(s): Fei Zhu, Mélissa Cizeron, Zhen Qiu, Ruth Benavides-Piccione, Maksym V. Kopanitsa, Nathan G. Skene, Babis Koniaris, Javier DeFelipe, Erik Fransén, Noboru H. Komiyama, Seth G.N. Grant
Published in: Neuron, Issue 99, 2018, Page(s) 781-799, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2018.07.007

A brain-wide atlas of synapses across the mouse lifespan

Author(s): Mélissa Cizeron, Zhen Qiu, Babis Koniaris, Ragini Gokhale, Noboru H. Komiyama, Erik Fransén, Seth G. N. Grant
Published in: Science, Issue 369, 2020, Page(s) eaba3163, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aba3163

A brain atlas of synapse protein lifetime across the mouse lifespan

Author(s): Edita Bulovaite, Zhen Qiu, Maximilian Kratschke, Adrianna Zgraj, David G. Fricker, Eleanor J. Tuck, Ragini Gokhale, Babis Koniaris, Shekib A. Jami, Paula Merino-Serrais, Elodie Husi, Lorena Mendive-Tapia, Marc Vendrell, Thomas J. O’Dell, Javier DeFelipe, Noboru H. Komiyama, Anthony Holtmaat, Erik Fransen, Seth G.N. Grant
Published in: Neuron, Issue 110, 2022, Page(s) 4057-4073, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2022.09.009

Developmental disruption and restoration of brain synaptome architecture in the murine Pax6 neurodevelopmental disease model

Author(s): Tomas-Roca L., Qiu Z., Fransén E., Gokhale R., Bulovaite E., Price D.J., Komiyama N.H., Grant S.G.N.
Published in: Nature Communications, Issue 13, 2022, Page(s) 6836, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-34131-w

Sleep maintains excitatory synapse diversity in the cortex and hippocampus

Author(s): Dimitra Koukaroudi, Zhen Qiu, Erik Fransén, Ragini Gokhale, Edita Bulovaite, Noboru H. Komiyama, Julie Seibt, Seth G.N. Grant
Published in: Current Biology, Issue 34, 2024, Page(s) 3836-3843.e5, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2024.07.032