Commercialisation of a world changing invention for the stabilisation and delivery of vaccines

Project Information

StableVax

Grant agreement ID: 696568

DOI

10.3030/696568

Project closed

EC signature date 24 August 2015

Start date 1 September 2015

End date 31 October 2015

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost

€ 71 429,00

EU contribution

€ 50 000,00

Coordinated by

STABLEPHARMA LIMITED
United Kingdom

Periodic Reporting for period 1 - StableVax (Commercialisation of a world changing invention for the stabilisation and delivery of vaccines)

Reporting period: 2015-09-01 to 2015-10-31

Summary of the context and overall objectives of the project

Stablepharma have developed a revolutionary vaccine stabilisation process incorporating an autodestruct syringe delivery system that has the capacity to make a significant contribution to world health by eliminating the costly and wasteful cold chain that is currently required to keep vaccines viable. The vaccine cold chain currently costs approximately €1m each day and can fail at any stage resulting in the wastage of over 50% of vaccines and more seriously, the potential for administration of ineffective vaccines.

Work performed from the beginning of the project to the end of the period covered by the report and main results achieved so far

The full economic and health consequences of such failures are significant and the Stablevax system will be a game-changing solution to this global problem.
We have undertaken a range of activities as part of our successful Phase 1 project and are now in a position to begin the final phase of work in readiness for product launch. Our process is fully patent protected in Africa and we have determined that we have full freedom to operate in this area. We have also reviewed the full specification of the process and the product required for protection. We have already begun an accelerated programme to ensure full protection in eleven international territories. As part of our regulatory obligations, we have contracted an expert, Dr Anil Chawla from Chimera Gentec, to direct our regulatory and commercialisation activities. He has many years’ experience in this field and in engaging with the World Health Organisation which will be one of our first customers. We have demonstrated that we have an acceptable yield rate of vaccine (>90%) after it has undergone the stabilisation process. This finding has been replicated in independent laboratories showing the consistency and reliability of our novel technology.

Progress beyond the state of the art and expected potential impact (including the socio-economic impact and the wider societal implications of the project so far)

As part of our Phase 2 project, we will progress up to 10 vaccines into pre-clinical testing to demonstrate the safety and efficacy of the stabilisation process. This will be rapidly followed by a clinical trial in human subjects. A plan for manufacture has also been developed as part of our Phase 1 project and we have draft design plans of the machinery required along with estimated costings. A full Business Plan has been prepared incorporating the outputs of the Phase 1 project outlined above, and details both technical and commercial goals including our best routes to market and a robust publicity strategy to ensure there is global awareness and uptake out the Stablevax system.

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