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Cancer Diagnosis by Multiplex Protein Epitope Profiling

Objective

Cancer incidence is continuously increasing, making it a major concern of European governments. Cheaper, more sensitive and specific diagnostic tests are needed to foster early cancer diagnosis, thereby alleviating the impact of cancer on citizens’ lives and reducing overall cancer care costs. BioSystems International Kft. (BSI) developed a diagnostics technology based on plasma protein epitome biomarker panels, with promising results to meet these needs for several cancers. BSI novel biomarkers-based in vitro diagnostics will bring better health outcomes for the patient as earlier detection will increase survival and will reduce overall care costs diagnosis contributing to the sustainability of the health care system. The CANDLE project objective is to consolidate the business plan and to complete clinical validation of the biomarker panels for breast and colon cancers, together representing 26.8 % of all cancer incidences in the EU. Clinically validated results obtained in CANDLE will enable BSI to seize the business opportunity and to maximize return on investments through higher royalties. BSI will license its cancer diagnostics intellectual property (IP) to fully integrated diagnostics companies who will get a competitive advantage by putting more cost-effective diagnostic products on the market. BSI already licensed its candidate diagnostic for lung cancer to a major European diagnostics company, demonstrating proof-of-concept for this business model. CANDLE will enable BSI to licence its IP after clinical validation at much better terms than for lung cancer, licensed at an earlier qualification stage. The global diagnostics market for cancers was estimated at 30 billion Euros in 2012. BSI’s IP-based diagnostics are expected to seize 4 % of this market within 10 years, resulting in more than 49.2 M€ of license revenues for BSI. CANDLE will boost BSI’s competitiveness and profitability, enabling the company to grow and to increase its innovation activity.

Field of science

  • /engineering and technology/medical engineering/medical laboratory technology/laboratory samples analysis
  • /medical and health sciences/clinical medicine/cancer/colorectal cancer
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins
  • /social sciences/other social sciences/social sciences interdisciplinary/sustainable development
  • /medical and health sciences/clinical medicine/cancer/breast cancer
  • /engineering and technology/medical engineering/medical laboratory technology/diagnostic technologies
  • /social sciences/economics and business/business and management/commerce

Call for proposal

H2020-SMEINST-1-2015
See other projects for this call

Funding Scheme

SME-1 - SME instrument phase 1

Coordinator

BIOSYSTEMS INTERNATIONAL KUTATO-, FEJLESZTO-, HASZNOSITO ES SZOLGALTATO KFT
Address
Nagyerdei Korut 98
4032 Debrecen
Hungary
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 50 000