Objective
ZipPrime has recently developed a novel magnetic nanoparticle (MNP)-based Next Generation Sequencing (NGS) library construction technology which not only improves the NGS-based clinical diagnostic and high-throughput genomics workflow, but also has the novel and unique benefit of facilitating the construction of reusable backup NGS libraries without any additional workload via the MNPs, enabling subsequent sequencing of the same nucleic acid samples. Utilizing MNPs, this technology creates a reusable backup template of the prepared NGS diagnostic library which can be sequenced with NGS diagnostic panels whenever required, even after long-term storage. MNP-based reusable NGS products can be adapted to the workflows of all currently available NGS platforms and NGS diagnostic panels as a reusable backup solution with long term storage capabilities and/or a proof-reading solution to test the same sample again to prevent a false negative or false positive NGS diagnostic test results. After the recent FDA premarket approval for clinical diagnostic applications of NGS platforms, a new era for NGS has begun. However, despite these recent developments, NGS platforms are still using the same pre-sequencing sample preparation and library construction methods that were developed and optimized for scientific research. Unlike academic research applications, clinical applications of NGS require a reusable proof-reading solution with the capacity to store the constructed library for testing the same sample again. Although there are several alternative methods and products for the construction and enrichment of sequencing libraries for NGS systems, there is no current product in the NGS-based clinical diagnostic market that is validated for clinical applications and has the option of constructing reusable storage libraries. The proposed project aims to clinically validate the MNP-based reusable NGS product pipeline developed by ZipPrime for use in clinical NGS applications.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences biochemistry biomolecules nucleic acids
- social sciences political sciences political policies civil society
- engineering and technology nanotechnology nano-materials
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being
MAIN PROGRAMME
See all projects funded under this programme -
H2020-EU.3.1.3. - Treating and managing disease
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-SMEInst-2014-2015
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
06520 Ankara
Türkiye
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.