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Implementation and Preliminary Validation of a Novel Noninvasive Neuromodulation Technique to Restore Hand Movement and Promote Recovery after Stroke

Objective

Stroke is a leading cause of adult chronic disability and has devastating socioeconomic costs. Severe hand paresis is a major contributor to chronic disability after stroke. New research opportunities offer the prospect of accelerating both the understanding of neurological disorders and the development of new therapies to improve rehabilitation by promoting neural plasticity. This project proposes an innovative multimodal platform integrating noninvasive electrophysiological recording and stimulation devices to “neuromodulate” the motor cortex. The platform will decode cortical states preceding human motor intentions to induce highly functional neural changes in the cortical circuits controlling hand muscles. I expect that the application of this new intervention will lead to unprecedented levels of motor recovery by reinforcing patients' remaining brain-muscle connections.

I recently finished my Ph.D. in the emerging field of neural engineering. In it I developed technologies to study brain activities related to voluntary and pathological motor processes in neurological patients, and I designed real-time platforms integrating cortical signals with muscle electrical stimulation for neurorehabilitation. The research in this project together with the expertise of my supervisor and host constitute an unmatchable opportunity for me to develop and consolidate critical neuroscience, neural engineering, and clinical skills, which will broaden my current competencies. I will also enrich my network of collaborations and receive training on management, tutoring, teaching, proposal writing and ethics, which will allow me to become and independent and mature researcher. I expect that my research will have high impact in the EU society and I anticipate that, through this fellowship, I will promote research in neuromodulation from a multidisciplinary perspective and devise the possibilities to effectively transfer new technologies to the clinical practice.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-EF-ST - Standard EF

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2015

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Coordinator

UNIVERSITY COLLEGE LONDON
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 195 454,80
Address
GOWER STREET
WC1E 6BT LONDON
United Kingdom

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Region
London Inner London — West Camden and City of London
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 195 454,80
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