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Regulation of (ADP-ribosyl)ation signalling in the DNA damage response: elucidating the function of a novel PARP1/ARTD1 interactor

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Publications

HPF1/C4orf27 Is a PARP-1-Interacting Protein that Regulates PARP-1 ADP-Ribosylation Activity

Author(s): Ian Gibbs-Seymour, Pietro Fontana, Johannes Gregor Matthias Rack, Ivan Ahel
Published in: Molecular Cell, 62/3, 2016, Page(s) 432-442, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2016.03.008

Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14

Author(s): Marion Schuller, Kerstin Riedel, Ian Gibbs-Seymour, Kristin Uth, Christian Sieg, André P. Gehring, Ivan Ahel, Franz Bracher, Benedikt M. Kessler, Jonathan M. Elkins, Stefan Knapp
Published in: ACS Chemical Biology, 12/11, 2017, Page(s) 2866-2874, ISSN 1554-8929
Publisher: American Chemical Society
DOI: 10.1021/acschembio.7b00445

MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response

Author(s): Christopher J. Staples, Giancarlo Barone, Katie N. Myers, Anil Ganesh, Ian Gibbs-Seymour, Abhijit A. Patil, Ryan D. Beveridge, Caroline Daye, Richard Beniston, Sarah Maslen, Ivan Ahel, J. Mark Skehel, Spencer J. Collis
Published in: Cell Reports, 16/10, 2016, Page(s) 2565-2575, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2016.07.087

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

Author(s): Dominika Kwasna, Syed Arif Abdul Rehman, Jayaprakash Natarajan, Stephen Matthews, Ross Madden, Virginia De Cesare, Simone Weidlich, Satpal Virdee, Ivan Ahel, Ian Gibbs-Seymour, Yogesh Kulathu
Published in: Molecular Cell, 2018, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2018.02.023

Serine ADP-Ribosylation Depends on HPF1

Author(s): Juan José Bonfiglio, Pietro Fontana, Qi Zhang, Thomas Colby, Ian Gibbs-Seymour, Ilian Atanassov, Edward Bartlett, Roko Zaja, Ivan Ahel, Ivan Matic
Published in: Molecular Cell, 65/5, 2017, Page(s) 932-940.e6, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2017.01.003