CORDIS - EU research results

Mechanisms of α-synuclein spreading, implications for synucleinopathies


α-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading

Author(s): Frida Loria, Jessica Y. Vargas, Luc Bousset, Sylvie Syan, Audrey Salles, Ronald Melki, Chiara Zurzolo
Published in: Acta Neuropathologica, Issue 134/5, 2017, Page(s) 789-808, ISSN 0001-6322
Publisher: Springer Verlag
DOI: 10.1007/s00401-017-1746-2

Tunneling nanotubes spread fibrillar α‐synuclein by intercellular trafficking of lysosomes

Author(s): Saïda Abounit, Luc Bousset, Frida Loria, Seng Zhu, Fabrice de Chaumont, Laura Pieri, Jean‐Christophe Olivo‐Marin, Ronald Melki, Chiara Zurzolo
Published in: The EMBO Journal, Issue 35/19, 2016, Page(s) 2120-2138, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.201593411

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