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Unlocking Triterpenoid Structural Diversity and Bioactivity through Genome Mining

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Diverged Plant Terpene Synthases Reroute the Carbocation Cyclization Path towards the Formation of Unprecedented 6/11/5 and 6/6/7/5 Sesterterpene Scaffolds

Author(s): Ancheng C. Huang, Young J. Hong, Andrew D. Bond, Dean J. Tantillo, Anne Osbourn
Published in: Angewandte Chemie International Edition, 57/5, 2018, Page(s) 1291-1295, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201711444

Harnessing plant metabolic diversity

Author(s): Charlie Owen, Nicola J Patron, Ancheng Huang, Anne Osbourn
Published in: Current Opinion in Chemical Biology, 40, 2017, Page(s) 24-30, ISSN 1367-5931
Publisher: Elsevier BV
DOI: 10.1016/j.cbpa.2017.04.015

Unearthing a sesterterpene biosynthetic repertoire in the Brassicaceae through genome mining reveals convergent evolution

Author(s): Ancheng C. Huang, Satria A. Kautsar, Young J. Hong, Marnix H. Medema, Andrew D. Bond, Dean J. Tantillo, Anne Osbourn
Published in: Proceedings of the National Academy of Sciences, 114/29, 2017, Page(s) E6005-E6014, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1705567114