Objective
This project ultimately aims to increase the crossover frequency in bread wheat (T. aestivum), which would result in a higher number of recombination events and would be a powerful tool for plant breeding. Thus the results of the proposed research are relevant to crop improvement as well as to human health. In the next 50 years, we will require as much wheat as has been produced since the beginning of agriculture. There are 1.5 billion dependent poor in the world, of which 300 million living in countries surrounding Europe are at risk of starvation in the future. Finding solutions to address the problems of wheat production will be a dominant topic in European plant science.
Specifically, this project builds on the work of the host group on the Ph1 locus - the major wheat locus controlling the specificity of chromosome pairing and recombination, and which ensures high fertility. Future breeding strategies for wheat will require exploitation of diversity in wild relatives, and manipulation of the Ph1 locus will be a powerful tool to facilitate introgression of traits from these related species. Recent work in the host group has shown that Ph1 locus carries cdk2-like kinases, and that deletion of Ph1 increases protein phosphorylation levels, altering the homologue pairing specificity. A major objective of this project is to characterise the alterations in the phospho-proteome of the meiocytes that result from deletion of the Ph1 locus. Recent results from a group studying meiosis in C. elegans have also shown that meiotic pairing specificity and recombination depend on protein phosphorylation levels, suggesting that the mechanism underlying Ph1 may be quite general. During this project we will collaborate with the C. elegans researchers to explore the similarities between the two kingdoms.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences genetics mutation
- natural sciences biological sciences genetics heredity
- natural sciences biological sciences genetics chromosomes
- natural sciences biological sciences botany
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
See all projects funded under this programme -
H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2015
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
NR4 7UH Norwich
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.