Objective
Polymer materials have outstanding properties with which to be applied for a wide range of applications. In particular, hydrogel materials are widely studied for applications in tissue engineering on account of their high water contents. Despite the advances in these materials, some biomedical targets remain challenging. Articular cartilage (AC) is the white flexible load-bearing soft tissue able to withstand the highest loads in physically demanding areas of the body. Once it is damaged, its poor ability for self-repair may induce a progressive loss of function that, ultimately, results in a severe musculoskeletal degenerative condition. While most commonly used hydrogel fabrication techniques still have practical limitations or do not lead to materials that are sufficiently strong for AC regeneration, the DN-Cartilogel project proposes the preparation of innovative tough, double network hydrogel materials that are based on advanced hydrophilic poly(carbonate)s. The tailored design of polymers with specific side-chain and end group functionalities will lead to hydrogel materials with improved mechanical strength, toughness and high water content. To this end, the project will apply the one-step synthetic methodology based on orthogonal click chemistry that was reported recently by the host group to generate novel and highly tunable materials. The ultimate goal is to develop a straightforward path to design robust DN hydrogels able to induce the differentiation of mesenchymal stem cells into specialized cartilage-producing cells, which directly addresses priorities established by the H2020 Work Programme.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences chemical sciences inorganic chemistry inorganic compounds
- medical and health sciences medical biotechnology tissue engineering
- natural sciences chemical sciences polymer sciences
- medical and health sciences medical biotechnology cells technologies stem cells
- engineering and technology industrial biotechnology biomaterials
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2015
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
B15 2TT Birmingham
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.