Objective Nature employs various polymerization processes (e.g. DNA replication, transcription and translation of proteins) in order to synthesize biopolymers such as DNA and proteins with controlled sequences and configurations. Such remarkable and complicated structures can fold into precise nanostructures via intramolecular and intermolecular interactions and thus replicating these domains via synthetic polymers has recently attracted considerable interest. The goal of BINAMA is to synthesize biomimicking nanostructure materials via intramolecular folding of sequence-controlled polymers in the presence of a “real” catalyst/chaperone, thus mimicking the intracellular environment. For the first part of the project, the sequence of functional monomers will be controlled utilizing controlled living radical polymerization methods. Subsequently, the incorporation of these monomers will induce hydrogen bonding, hydrophobic/hydrophobic, pi-pi, charge and disulphide interactions typically employed by proteins in order to facilitate the controlled folding of the polymer chains, adopting natural motifs and patterns. The ability to mimic these perfectly defined sequence-controlled polymers (e.g. DNA and proteins) via synthetic polymer chemistry will pave the way for synthetic bioanalogues and could also enhance their functions and properties. Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural scienceschemical sciencespolymer sciencesnatural scienceschemical sciencesinorganic chemistryhalogensnatural scienceschemical sciencescatalysisnatural scienceschemical sciencesorganic chemistryamines Keywords sequence controlled polymers biomimicking materials intra and intermolecular interactions ATRP RAFT Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2015-GF - Marie Skłodowska-Curie Individual Fellowships (IF-GF) Call for proposal H2020-MSCA-IF-2015 See other projects for this call Funding Scheme MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF) Coordinator THE UNIVERSITY OF WARWICK Net EU contribution € 211 825,20 Address Kirby corner road - university house CV4 8UW Coventry United Kingdom See on map Region West Midlands (England) West Midlands Coventry Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Partners (1) Sort alphabetically Sort by Net EU contribution Expand all Collapse all Partner Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. THE REGENTS OF THE UNIVERSITY OF CALIFORNIA United States Net EU contribution € 0,00 Address Franklin street 1111 12 floor 94607 Oakland ca See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 120 097,80
