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Mapping bacterial division in Bacillus subtilis

Objective

The bacterial cell cycle is of fundamental importance and an important potential antibiotic target; however, many details of
the molecular mechanisms involved remain elusive. Sporulation in Bacillus subtilis is an important model system for cell
cycle studies. Here, I propose applying the ribosome profiling method, not only to identify novel factors involved in the of B.
subtilis cell cycle, but also to create a map of factors regulating this process. I will use advanced genetic methods and
microscopic techniques to characterize the functions of the novel factors, gaining insights into their role in the cell cycle. My
extensive experience in prokaryotic translation gained in the laboratory of Dr. Daniel Wilson in Munich, Germany, combined
with the exceptional genetics and cell biology expertise of the laboratory of Prof. Jeff Errington in Newcastle, England,
creates a great opportunity to study important fundamental aspects of bacteria, with potential implications for healthcare,
drug discovery and industrial biotechnology, as well as providing the foundation for a successful independent career in
science.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2015

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Coordinator

UNIVERSITY OF NEWCASTLE UPON TYNE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 183 454,80
Address
KINGS GATE
NE1 7RU Newcastle Upon Tyne
United Kingdom

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Region
North East (England) Northumberland and Tyne and Wear Tyneside
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 183 454,80
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