Innovative Strategies towards Halogenated Organic Molecules: From Reaction Design to Application in Drug Synthesis

Project Information

HALODRUGSYN

Grant agreement ID: 714049

DOI 10.3030/714049

Project closed

EC signature date 17 October 2016

Start date 1 February 2017

End date 31 January 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 496 664,30

EU contribution € 1 496 664,30

Coordinated by

UNIVERSITAET INNSBRUCK
Austria

Publications

Peer reviewed articles (8)

Total Synthesis of Oxepin and Dihydrooxepin Containing Natural Products

Author(s): Kevin Rafael Sokol, Thomas Magauer
Published in: Synthesis, 2021, ISSN 0039-7881
Publisher: Georg Thieme Verlag
DOI: 10.1055/s-0037-1610776

Ring Expansion of 1-Indanones to 2-Halo-1-naphthols as an Entry Point to Gilvocarcin Natural Products

Author(s): Ivica Zamarija, Benjamin J. Marsh, Thomas Magauer
Published in: Organic Letters, 2021, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.1c03530

A modular synthesis of tetracyclic meroterpenoid antibiotics

Author(s): Raphael Wildermuth, Klaus Speck, Franz-Lucas Haut, Peter Mayer, Bianka Karge, Mark Brönstrup, Thomas Magauer
Published in: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-017-02061-7

De Novo Synthesis of Benzannelated Heterocycles

Author(s): Johannes Feierfeil, Thomas Magauer
Published in: Chemistry - A European Journal, Issue 24/6, 2018, Page(s) 1455-1458, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201705662

9-Membered Carbocycles: Strategies and Tactics for their Synthesis

Author(s): Raphael Ernst Wildermuth, Tatjana Huber, Thomas Magauer
Published in: Chemistry - A European Journal, 2017, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201705919

Total Synthesis of Salimabromide: A Tetracyclic Polyketide from a Marine Myxobacterium

Author(s): Matthias Schmid, Adriana S. Grossmann, Klaus Wurst, Thomas Magauer
Published in: Journal of the American Chemical Society, 2018, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.8b06228

Ring-expansion approaches for the total synthesis of salimabromide

Author(s): Matthias Schmid, Adriana S. Grossmann, Peter Mayer, Thomas Müller, Thomas Magauer
Published in: Tetrahedron, Issue 75/24, 2019, Page(s) 3195-3215, ISSN 0040-4020
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.tet.2019.03.010

Synthesis of Vicinal Quaternary All-Carbon Centers via Acid-catalyzed Cycloisomerization of Neopentylic Epoxides

Author(s): Matthias Schmid, Kevin R. Sokol, Lukas A. Wein, Sofia Torres Venegas, Christina Meisenbichler, Klaus Wurst, Maren Podewitz, Thomas Magauer
Published in: Organic Letters, 2020, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.0c02296