Skip to main content
European Commission logo
English English
CORDIS - EU research results
CORDIS
CORDIS Web 30th anniversary CORDIS Web 30th anniversary

Characterisation of DNA Double-Strand Break Repair by Alternative End-Joining: Potential Targets for Cancer Therapy

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors

Author(s): Jia Zhou, Camille Gelot , Constantia Pantelidou, Adam Li, Hatice Yücel, Rachel E Davis, Anniina Farkkila, Bose Kochupurakkal, Aleem Syed, Geoffrey I Shapiro, John A Tainer, Brian S J Blagg, Raphael Ceccaldi, Alan D D'Andrea
Published in: Nature Cancer, 2021, Page(s) 598–610., ISSN 2662-1347
Publisher: Springer Nature
DOI: 10.1038/s43018-021-00203-x

DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of Lamin A/C

Author(s): Kovacs M.T, Vallette M, Wiertsema P, Dingli F, Loew D, Nader G.P, Piel M, Ceccaldi R
Published in: Molecular Cell, 2023, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2023.09.023

Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis

Author(s): Gelot C, Kovacs M.T, Miron S, Mylne E, Ghouil R, Popova T, Dingli F, Loew D, Guirouilh-Barbat J, Del Nery E, Zinn S and Ceccaldi R
Published in: Nature, 2023, Page(s) Sept 6. 621, 415–422, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-023-06506-6

FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair

Author(s): Zeina Kais, Beatrice Rondinelli, Amie Holmes, Colin O’Leary, David Kozono, Alan D. D’Andrea, Raphael Ceccaldi
Published in: Cell Reports, Issue 15/11, 2016, Page(s) 2488-2499, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2016.05.031

Intellectual Property Rights

COMPOUNDS AND METHODS FOR TREATING CANCER

Application/Publication number: 20 18056080
Date: 2018-10-16

COMPOUNDS AND METHODS FOR TREATING CANCER

Application/Publication number: 20 18056080
Date: 2018-10-16
Applicant(s): INSTITUT CURIE

Searching for OpenAIRE data...

There was an error trying to search data from OpenAIRE

No results available