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T6SS MIX-effectors: secretion, activities and use as antibacterial treatment

Publications

Formylglycine-generating enzyme-like proteins constitute a novel family of widespread type VI secretion system immunity proteins

Author(s): Juvenal Lopez, Nguyen-Hung Le, Ki Hwan Moon, Dor Salomon, Eran Bosis, Mario F. Feldman
Published in: Journal of Bacteriology, 2021, ISSN 0021-9193
Publisher: American Society for Microbiology
DOI: 10.1128/jb.00281-21

The RIX domain defines a class of polymorphic T6SS effectors and secreted adaptors

Author(s): Katarzyna Kanarek, Chaya Mushka Fridman, Eran Bosis, Dor Salomon
Published in: Nature Communications, Issue 14, 2023, Page(s) 4983, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-40659-2

A binary effector module secreted by a type VI secretion system

Author(s): Yasmin Dar, Biswanath Jana, Eran Bosis, Dor Salomon
Published in: EMBO reports, Issue 14693178, 2022, Page(s) 23:e53981, ISSN 1469-3178
Publisher: EMBO press
DOI: 10.15252/embr.202153981

A DNase Type VI Secretion System Effector Requires Its MIX Domain for Secretion

Author(s): Chaya Mushka Fridman; Biswanath Jana; Rotem Ben-Yaakov; Eran Bosis; Dor Salomon
Published in: Microbiology Spectrum, Issue 1, 2022, ISSN 2165-0497
Publisher: American Society for Microbiology
DOI: 10.1128/spectrum.02465-22

Multiple T6SSs, Mobile Auxiliary Modules, and Effectors Revealed in a Systematic Analysis of the Vibrio parahaemolyticus Pan-Genome

Author(s): Biswanath Jana, Kinga Keppel, Chaya Mushka Fridman, Eran Bosis, Dor Salomon
Published in: mSystems, Issue Vol. 7, No. 6, 2022, ISSN 2379-5077
Publisher: American Society for Microbiology
DOI: 10.1128/msystems.00723-22

A novel class of polymorphic toxins in Bacteroidetes

Author(s): Biswanath Jana, Dor Salomon, Eran Bosis
Published in: Life Science Alliance, Issue 3/4, 2020, Page(s) e201900631, ISSN 2575-1077
Publisher: EMBO Press
DOI: 10.26508/lsa.201900631

Type VI secretion system MIX‐effectors carry both antibacterial and anti‐eukaryotic activities

Author(s): Ann Ray, Nika Schwartz, Marcela de Souza Santos, Junmei Zhang, Kim Orth, Dor Salomon
Published in: EMBO reports, Issue 18/11, 2017, Page(s) 1978-1990, ISSN 1469-221X
Publisher: Nature Publishing Group
DOI: 10.15252/embr.201744226

The Antibacterial and Anti-Eukaryotic Type VI Secretion System MIX-Effector Repertoire in Vibrionaceae

Author(s): Yasmin Dar, Dor Salomon, Eran Bosis
Published in: Marine Drugs, Issue 16/11, 2018, Page(s) 433, ISSN 1660-3397
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/md16110433

The regulatory network of Vibrio parahaemolyticus type VI secretion system 1

Author(s): Rotem Ben‐Yaakov, Dor Salomon
Published in: Environmental Microbiology, Issue Volume21, Issue7 July 2019, 2019, Page(s) 2248-2260, ISSN 1462-2912
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.14594

A modular effector with a DNase domain and a marker for T6SS substrates

Author(s): Biswanath Jana, Chaya M. Fridman, Eran Bosis, Dor Salomon
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-11546-6

Type VI secretion system: a modular toolkit for bacterial dominance

Author(s): Biswanath Jana, Dor Salomon
Published in: Future Microbiology, 2019, ISSN 1746-0913
Publisher: Future Medicine Ltd.
DOI: 10.2217/fmb-2019-0194

A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors

Author(s): Chaya M. Fridman, Kinga Keppel, Motti Gerlic, Eran Bosis, Dor Salomon
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-14951-4

A phage mechanism for selective nicking of dUMP-containing DNA

Author(s): Tridib Mahata, Shahar Molshanski-Mor, Moran G. Goren, Biswanath Jana, Miriam Kohen-Manor, Ido Yosef, Oren Avram, Tal Pupko, Dor Salomon, Udi Qimron
Published in: Proceedings of the National Academy of Sciences, Issue 118/23, 2021, Page(s) e2026354118, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2026354118

Engineering a customizable antibacterial T6SS-based platform in Vibrio natriegens

Author(s): Biswanath Jana, Kinga Keppel, Dor Salomon
Published in: EMBO reports, 2021, Page(s) 22:e53681, ISSN 1469-3178
Publisher: EMBO press
DOI: 10.15252/embr.202153681

MIX-Effectors – T6SS MIX-effectors: secretion, activities and use as antibacterial treatment – ERC

Author(s): Dor Salomon
Published in: Impact, Issue 2018/12, 2018, Page(s) 9-11, ISSN 2398-7073
Publisher: Science Impact Ltd
DOI: 10.21820/23987073.2018.12.9

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