Quantifying behavioural phenotype space: chemistry-to-gene screens and combination therapies

Publications

Other (1)

Megapixel camera arrays for high-resolution animal tracking in multiwell plates

Author(s): Ida Barlow, Luigi Feriani, Eleni Minga, Adam McDermott-Rouse, Thomas O’Brien, Ziwei Liu, Maximilian Hofbauer, John R. Stowers, Erik C. Andersen, Siyu Serena Ding, André E.X. Brown
Published in: bioRxiv, 2021
Publisher: bioRxiv
DOI: 10.1101/2021.04.16.440222

Peer reviewed articles (4)

Behavioral fingerprints predict insecticide and anthelmintic mode of action

Author(s): Adam McDermott‐Rouse, Eleni Minga, Ida Barlow, Luigi Feriani, Philippa H Harlow, Anthony J Flemming, André E X Brown
Published in: Molecular Systems Biology, 17/5, 2021, ISSN 1744-4292
Publisher: Nature Publishing Group
DOI: 10.15252/msb.202110267

Powerful and interpretable behavioural features for quantitative phenotyping of Caenorhabditis elegans

Author(s): Avelino Javer, Lidia Ripoll-Sánchez, André E.X. Brown
Published in: Philosophical Transactions of the Royal Society B: Biological Sciences, 373/1758, 2018, Page(s) 20170375, ISSN 0962-8436
Publisher: Royal Society of London
DOI: 10.1098/rstb.2017.0375

Bi-allelic loss-of-function variants in PPFIBP1 cause a neurodevelopmental disorder with microcephaly, epilepsy, and periventricular calcifications

Author(s): Erik Rosenhahn, Thomas J O'Brien, Maha S Zaki, Ina Sorge, Dagmar Wieczorek, Kevin Rostasy, Antonio Vitobello, Sophie Nambot, Fowzan S Alkuraya, Mais O Hashem, Amal Alhashem, Brahim Tabarki, Abdullah S Alamri, Ayat H Al Safar, Dalal K Bubshait, Nada F Alahmady, Joseph G Gleeson, Mohamed S Abdel-Hamid, Nicole Lesko, Sofia Ygberg, Sandrina P Correia, Anna Wredenberg, Shahryar Alavi, Seyed M Seyedhass
Published in: American Journal of Human Genetics, 2022, ISSN 1537-6605
Publisher: Cell Press
DOI: 10.1016/j.ajhg.2022.06.008

Megapixel camera arrays enable high-resolution animal tracking in multiwell plates

Author(s): Ida L. Barlow, Luigi Feriani, Eleni Minga, Adam McDermott-Rouse, Thomas James O’Brien, Ziwei Liu, Maximilian Hofbauer, John R. Stowers, Erik C. Andersen, Siyu Serena Ding, André E. X. Brown
Published in: Communications Biology, 5, 2022, Page(s) 253, ISSN 2399-3642
Publisher: Springer Nature
DOI: 10.1038/s42003-022-03206-1