Age-dependent Regulation of Dendritic Cell Development and Function

Project Information

Baby DCs

Grant agreement ID: 715182

DOI

10.3030/715182

Project closed

EC signature date 7 December 2016

Start date 1 June 2017

End date 31 December 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (13)

One concept does not fit all: the immune system in different forms of acute kidney injury.

Author(s): Hans-Joachim Anders; Louise Wilkens; Barbara U. Schraml; Julian A. Marschner
Published in: Nephrology Dialysis Transplantation, Issue 1, 2021, ISSN 1460-2385
Publisher: Oxfod Academic
DOI: 10.1093/ndt/gfaa056

RORγt-expressing dendritic cells are functionally versatile and evolutionarily conserved antigen-presenting cells

Author(s): Hamsa Narasimhan, Maria L. Richter, Ramin Shakiba, Nikos E. Papaioannou, Christina Stehle, Kaushikk Ravi Rengarajan, Isabel Ulmert, Arek Kendirli, Clara de la Rosa, Pin-Yu Kuo, Abigail Altman, Philipp Münch, Saba Mahboubi, Vanessa Küntzel, Amina Sayed, Eva-Lena Stange, Jonas Pes, Alina Ulezko Antonova, Carlos-Filipe Pereira, Ludger Klein, Diana Dudziak, Marco Colonna, Natalia Torow, Mathias W. H
Published in: Proceedings of the National Academy of Sciences, Issue 122, 2025, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2417308122

Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses

Author(s): Hongkui Xiao, Isabel Ulmert, Luisa Bach, Johanna Huber, Hamsa Narasimhan, Ilia Kurochkin, Yinshui Chang, Signe Holst, Urs Mörbe, Lili Zhang, Andreas Schlitzer, Carlos-Filipe Pereira, Barbara U. Schraml, Dirk Baumjohann, Katharina Lahl
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-46966-6

Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice

Author(s): Papaioannou NE, Salei N, Rambichler S, Ravi K, Popovic J, Küntzel V, Lehmann CHK, Fiancette R, Salvermoser J, Gajdasik DW, Mettler R, Messerer D, Carrelha J, Ohnmacht C, Haller D, Stumm R, Straub T, Jacobsen SEW, Schulz C, Withers DR, Schotta G, Dudziak D, Schraml BU
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-20659-2

Loss of direct adrenergic innervation after peripheral nerve injury causes lymph node expansion through IFN-γ

Author(s): Chien-Sin Chen; Jasmin Weber; Stephan Jonas Holtkamp; Louise Madeleine Ince; Alba de Juan; Chen Wang; Lydia Lutes; Coline Barnoud; Burak Kizil; Sophia Martina Hergenhan; Johanna Salvermoser; Manuel Lasch; Elisabeth Deindl; Barbara Schraml; Dirk Baumjohann; Christoph Scheiermann
Published in: The Journal of Experimental Medicine, Issue 1, 2021, ISSN 1540-9538
Publisher: Rockefeller University press
DOI: 10.1084/jem.20202377

Guidelines for visualization and analysis of DC in tissues using multiparameter fluorescence microscopy imaging methods

Author(s): Felix Bayerl, David A. Bejarano, Giulia Bertacchi, Anne‐Claire Doffin, Elisa Gobbini, Margaux Hubert, Lijian Li, Philippa Meiser, Anna‐Marie Pedde, Wilfried Posch, Luise Rupp, Andreas Schlitzer, Marc Schmitz, Barbara U. Schraml, Stefan Uderhardt, Jenny Valladeau‐Guilemond, Doris Wilflingseder, Viktoria Zaderer, Jan P. Böttcher
Published in: European Journal of Immunology, Issue 53, 2023, ISSN 0014-2980
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202249923

Selective depletion of a CD64-expressing phagocyte subset mediates protection against toxic kidney injury and failure

Author(s): Natallia Salei, Xingqi Ji, View ORCID ProfileDalia Pakalniškytė, Vanessa Kuentzel, Stephan Rambichler, View ORCID ProfileNa Li, Markus Moser, View ORCID ProfileKatja Steiger, View ORCID ProfileThorsten Buch, Hans-Joachim Anders, and View ORCID ProfileBarbara U. Schraml
Published in: Proceedings of the National Academy of Sciences, 2021, ISSN 1091-6490
Publisher: PNAS
DOI: 10.1073/pnas.2022311118

Interleukin-10 enhances recruitment of immune cells in the neonatal mouse model of obstructive nephropathy

Author(s): Maja Wyczanska, Franziska Thalmeier, Ursula Keller, Richard Klaus, Hamsa Narasimhan, Xingqi Ji, Barbara U. Schraml, Lou M. Wackerbarth, Bärbel Lange-Sperandio
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-55469-9

Clec9a-Mediated Ablation of Conventional Dendritic Cells Suggests a Lymphoid Path to Generating Dendritic Cells In Vivo

Author(s): Johanna Salvermoser, Janneke van Blijswijk, Nikos E. Papaioannou, Stephan Rambichler, Maria Pasztoi, Dalia Pakalniškytė, Neil C. Rogers, Selina J. Keppler, Tobias Straub, Caetano Reis e Sousa, Barbara U. Schraml
Published in: Frontiers in Immunology, Issue 9, 2018, Page(s) https://www.frontiersin.org/articles/10.3389/fimmu.2018.00699/full, ISSN 1664-3224
Publisher: Frontiers in Immunology
DOI: 10.3389/fimmu.2018.00699

Understanding the Functional Properties of Neonatal Dendritic Cells: A Doorway to Enhance Vaccine Effectiveness?

Author(s): Nikos E. Papaioannou, Maria Pasztoi, Barbara U. Schraml
Published in: Frontiers in Immunology, Issue 9, 2019, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2018.03123

The Kidney Contains Ontogenetically Distinct Dendritic Cell and Macrophage Subtypes throughout Development That Differ in Their Inflammatory Properties

Author(s): Natallia Salei, Stephan Rambichler, Johanna Salvermoser, Nikos E. Papaioannou, Ronja Schuchert, Dalia Pakalniškytė, Na Li, Julian A. Marschner, Julia Lichtnekert, Christopher Stremmel, Filippo M. Cernilogar, Melanie Salvermoser, Barbara Walzog, Tobias Straub, Gunnar Schotta, Hans-Joachim Anders, Christian Schulz, Barbara U. Schraml
Published in: Journal of the American Society of Nephrology, Issue https://jasn.asnjournals.org/content/31/2/257.abstract, 2020, Page(s) ASN.2019040419, ISSN 1046-6673
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/asn.2019040419

NR2F6 regulates stem cell hematopoiesis and myelopoiesis in mice

Author(s): Johannes Woelk, Hamsa Narasimhan, Christa Pfeifhofer-Obermair, Barbara U. Schraml, Natascha Hermann-Kleiter
Published in: Frontiers in Immunology, Issue 15, 2025, ISSN 1664-3224
Publisher: Frontiers in Immunology
DOI: 10.3389/fimmu.2024.1404805

IRF8-Dependent Type I Conventional Dendritic Cells (cDC1s) Control Post-Ischemic Inflammation and Mildly Protect Against Post-Ischemic Acute Kidney Injury and Disease.

Author(s): Li N, Steiger S, Fei L, Li C, Shi C, Salei N, Schraml BU, Zheng Z, Anders HJ, Lichtnekert J.
Published in: Frontiers in Immunology, 2021, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2021.685559