Objective In natural and agricultural habitats, plants grow in organismal communities and therefore have to compete for limited resources. Competition between different crop plants and between crops and weeds leads to losses of potential agricultural product and requires heavy use of fertilizer and herbicides, with negative effects for the environment and human health. Plants have evolved various strategies to outcompete their neighbours and to secure their access to resources; one of them is the release of toxic chemical compounds into the soil that interfere with the growth of neighbouring plants. Many of today’s major crops, such as wheat, rye and maize, produce phytotoxins. Conversely, crop species also suffer from chemical attack by other plants growing in their vicinity. Although many of the chemical compounds applied in this biochemical warfare have been identified, we know little about how they act in the target plant; neither do we understand how some plant species are able to tolerate this chemical attack.FEAR-SAP studies the genetic architecture that underlies biochemical plant-plant interference and the evolution of weed resistance to crop-released phytotoxins. To this end it employs a comprehensive array of molecular genetics, genomics and metagenomics analyses, unprecedented in the research on plant-plant competition. The aims of FEAR-SAP are to uncover the molecular targets of plant-derived phytotoxins and to identify the genetic components that are essential for tolerance to these substances. Moreover, FEAR-SAP investigates how the microbial community that is associated with the plant might enhance efficiency of the donor and/or mediate tolerance of the target plant. Ultimately, we will use this information to explore intelligent engineering of more refined and competitive crops, which will be at the foundation of efficient and ecologically responsible weed control and improved crop rotation strategies. Fields of science agricultural sciencesagriculture, forestry, and fisheriesagricultureagronomyplant protection Keywords Plant-plant competition Allelopathy Microbiome Population genomics Chromatin Programme(s) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Topic(s) ERC-2016-STG - ERC Starting Grant Call for proposal ERC-2016-STG See other projects for this call Funding Scheme ERC-STG - Starting Grant Host institution LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN Net EU contribution € 916 786,68 Address GESCHWISTER SCHOLL PLATZ 1 80539 Muenchen Germany See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 916 786,68 Beneficiaries (2) Sort alphabetically Sort by Net EU contribution Expand all Collapse all LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN Germany Net EU contribution € 916 786,68 Address GESCHWISTER SCHOLL PLATZ 1 80539 Muenchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 916 786,68 GREGOR MENDEL INSTITUT FUR MOLEKULARE PFLANZENBIOLOGIE GMBH Participation ended Austria Net EU contribution € 583 213,32 Address DR BOHR GASSE 3 1030 Wien See on map Region Ostösterreich Wien Wien Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 583 213,32