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Imaging and detection of tumor-associated glycan structures on tumor cells

Deliverables

Produce a project poster and a presentation

Produce a project poster and a presentation

Produce a minimum of 2 press releases

Produce a minimum of 2 press releases

Project website launched

Project website launched

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Publications

The GAGOme: a cell-based library of displayed glycosaminoglycans

Author(s): Yen-Hsi Chen, Yoshiki Narimatsu, Thomas M. Clausen, Catarina Gomes, Richard Karlsson, Catharina Steentoft, Charlotte B. Spliid, Tobias Gustavsson, Ali Salanti, Andrea Persson, Anders Malmström, Daniel Willén, Ulf Ellervik, Eric P. Bennett, Yang Mao, Henrik Clausen, Zhang Yang
Published in: Nature Methods, Issue 15/11, 2018, Page(s) 881-888, ISSN 1548-7091
DOI: 10.1038/s41592-018-0086-z

Determination of cytokine regulated glycan expression by using molecularly imprinted polymers targeting sialic acid

Author(s): Yuecheng Zhang, Kushtrim Llapashtica, Sudhirkumar Shinde, Borje Sellergren, Zahra El-Schich, Anette Gjorloff Wingren
Published in: Journal of Cancer Metastasis and Treatment, Issue 2019, 2019, ISSN 2454-2857
DOI: 10.20517/2394-4722.2018.112

An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

Author(s): Yoshiki Narimatsu, Hiren J. Joshi, Rebecca Nason, Julie Van Coillie, Richard Karlsson, Lingbo Sun, Zilu Ye, Yen-Hsi Chen, Katrine T. Schjoldager, Catharina Steentoft, Sanae Furukawa, Barbara A. Bensing, Paul M. Sullam, Andrew J. Thompson, James C. Paulson, Christian Büll, Gosse J. Adema, Ulla Mandel, Lars Hansen, Eric Paul Bennett, Ajit Varki, Sergey Y. Vakhrushev, Zhang Yang, Henrik Clausen
Published in: Molecular Cell, Issue 75/2, 2019, Page(s) 394-407.e5, ISSN 1097-2765
DOI: 10.1016/j.molcel.2019.05.017

γ‐(S)‐Guanidinylmethyl Modified Triplex‐Forming Peptide Nucleic Acids Increase Hoogsteen‐Face Affinity for a MicroRNA and Enhance Cellular Uptake

Author(s): Ville Tähtinen, Alejandra Verhassel, Johanna Tuomela, Pasi Markus Virta
Published in: ChemBioChem, 2019, ISSN 1439-4227
DOI: 10.1002/cbic.201900393

Engineering mammalian cells to produce plant-specific N-glycosylation on proteins

Author(s): Joachim Steen Larsen, Richard Torbjörn Gustav Karlsson, Weihua Tian, Morten Alder Schulz, Annemarie Matthes, Henrik Clausen, Bent Larsen Petersen, Zhang Yang
Published in: Glycobiology, 2020, ISSN 1460-2423
DOI: 10.1093/glycob/cwaa009

The functional interlink between AR and MMP9/VEGF signaling axis is mediated through PIP5K1α/pAKT in prostate cancer

Author(s): Per Larsson, Azharuddin Sajid Syed Khaja, Julius Semenas, Tianyan Wang, Martuza Sarwar, Nishtman Dizeyi, Athanasios Simoulis, Andreas Hedblom, Sun Nyunt Wai, Niels Ødum, Jenny L. Persson
Published in: International Journal of Cancer, Issue 146/6, 2019, Page(s) 1686-1699, ISSN 0020-7136
DOI: 10.1002/ijc.32607

Different isolation approaches lead to diverse glycosylated extracellular vesicle populations

Author(s): Daniela Freitas, Meritxell Balmaña, Juliana Poças, Diana Campos, Hugo Osório, Andriana Konstantinidi, Sergey Y. Vakhrushev, Ana Magalhães, Celso A. Reis
Published in: Journal of Extracellular Vesicles, Issue 8/1, 2019, Page(s) 1621131, ISSN 2001-3078
DOI: 10.1080/20013078.2019.1621131

Digital holographic cytometry - Macrophage uptake of nanoprobes

Author(s): Louise Sternbæk, Martha Wamaitha Kimani, Kornelia Gawlitza Birgit Janicke, Kersti Alm, and Anette Gjörloff Wingren
Published in: Imaging&Microscopy, Issue 1, 2019, Page(s) 21-23