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TIGIT therapy for cancer treatment

Publications

Decay of the Stress-Induced Ligand MICA Is Controlled by the Expression of an Alternative 3′ Untranslated Region

Author(s): Tirtsah Toledano, Alon Vitenshtein, Noam Stern-Ginossar, Einat Seidel, Ofer Mandelboim
Published in: The Journal of Immunology, Issue 200/8, 2018, Page(s) 2819-2825, ISSN 0022-1767
DOI: 10.4049/jimmunol.1700968

The Human Cytomegalovirus Protein UL148A Downregulates the NK Cell-Activating Ligand MICA To Avoid NK Cell Attack

Author(s): Liat Dassa, Einat Seidel, Esther Oiknine-Djian, Rachel Yamin, Dana G. Wolf, Vu Thuy Khanh Le-Trilling, Ofer Mandelboim
Published in: Journal of Virology, Issue 92/17, 2018, ISSN 0022-538X
DOI: 10.1128/jvi.00162-18

Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies

Author(s): Moriya Gamliel, Debra Goldman-Wohl, Batya Isaacson, Chamutal Gur, Natan Stein, Rachel Yamin, Michael Berger, Myriam Grunewald, Eli Keshet, Yoach Rais, Chamutal Bornstein, Eyal David, Adam Jelinski, Iris Eisenberg, Caryn Greenfield, Arbel Ben-David, Tal Imbar, Ronit Gilad, Ronit Haimov-Kochman, David Mankuta, Matan Elami-Suzin, Ido Amit, Jacob H. Hanna, Simcha Yagel, Ofer Mandelboim
Published in: Immunity, Issue 48/5, 2018, Page(s) 951-962.e5, ISSN 1074-7613
DOI: 10.1016/j.immuni.2018.03.030

Human cytomegalovirus escapes immune recognition by NK cells through the downregulation of B7-H6 by the viral genes US18 and US20

Author(s): Yoav Charpak-Amikam, Tobias Kubsch, Einat Seidel, Esther Oiknine-Djian, Noemi Cavaletto, Rachel Yamin, Dominik Schmiedel, Dana Wolf, Giorgio Gribaudo, Martin Messerle, Luka Cicin-Sain, Ofer Mandelboim
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
DOI: 10.1038/s41598-017-08866-2

NKp46 Receptor-Mediated Interferon-γ Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis

Author(s): Ariella Glasner, Assi Levi, Jonatan Enk, Batya Isaacson, Sergey Viukov, Shari Orlanski, Alon Scope, Tzahi Neuman, Claes D. Enk, Jacob H. Hanna, Veronika Sexl, Stipan Jonjic, Barbara Seliger, Laurence Zitvogel, Ofer Mandelboim
Published in: Immunity, Issue 48/1, 2018, Page(s) 107-119.e4, ISSN 1074-7613
DOI: 10.1016/j.immuni.2017.12.007

Disarming Cellular Alarm Systems—Manipulation of Stress-Induced NKG2D Ligands by Human Herpesviruses

Author(s): Dominik Schmiedel, Ofer Mandelboim
Published in: Frontiers in Immunology, Issue 8, 2017, ISSN 1664-3224
DOI: 10.3389/fimmu.2017.00390