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Synaptic dysfunction in Neurodegenerative Diseases

Deliverables

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Publications

Contribution of the astrocytic tau pathology to synapse loss in progressive supranuclear palsy and corticobasal degeneration

Author(s): Nils Briel, Katrin Pratsch, Sigrun Roeber, Thomas Arzberger, Jochen Herms
Published in: Brain Pathology, 31/4, 2021, Page(s) e12914, ISSN 1015-6305
Publisher: International Society of Neuropathology
DOI: 10.1111/bpa.12914

VAMP4 Controls Constitutive Recycling and Sorting of Post-Synaptic Receptors in Neuronal Dendrites

Author(s): May Bakr, Damien Jullié, Julia Krapivkina, Lou Bouit, Jennifer Petersen, Natacha Retailleau, Christelle Breillat, Daniel Choquet, David Perrais
Published in: SSRN Electronic Journal, 2021, ISSN 1556-5068
Publisher: Cell Press
DOI: 10.2139/ssrn.3762644

The Links between ALS and NF-κB

Author(s): Emma Källstig, Brian D. McCabe, Bernard L. Schneider
Published in: International Journal of Molecular Sciences, 22/8, 2021, Page(s) 3875, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22083875

FRET-Based Screening Identifies p38 MAPK and PKC Inhibition as Targets for Prevention of Seeded α-Synuclein Aggregation

Author(s): Alexander Svanbergsson, Fredrik Ek, Isak Martinsson, Jordi Rodo, Di Liu, Edoardo Brandi, Caroline Haikal, Laura Torres-Garcia, Wen Li, Gunnar Gouras, Roger Olsson, Tomas Björklund, Jia-Yi Li
Published in: Neurotherapeutics, Online ahead of print, 2021, Page(s) not available, ISSN 1933-7213
Publisher: Elsevier BV
DOI: 10.1007/s13311-021-01070-1

Glycation in Huntington’s Disease: A Possible Modifier and Target for Intervention

Author(s): Inês Caldeira Brás, Annekatrin König, Tiago Fleming Outeiro
Published in: Journal of Huntington's Disease, 8/3, 2019, Page(s) 245-256, ISSN 1879-6397
Publisher: IOS Press
DOI: 10.3233/jhd-190366

Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies

Author(s): Inês C. Brás, Tiago F. Outeiro
Published in: Cells, 10/2, 2021, Page(s) 375, ISSN 2073-4409
Publisher: PMC
DOI: 10.3390/cells10020375

Sensing α-Synuclein From the Outside via the Prion Protein: Implications for Neurodegeneration

Author(s): Inês Caldeira Brás, Luísa V. Lopes, Tiago Fleming Outeiro
Published in: Movement Disorders, 33/11, 2018, Page(s) 1675-1684, ISSN 0885-3185
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/mds.27478

Identification of novel protein phosphatases as modifiers of alpha-synuclein aggregation in yeast

Author(s): Inês Caldeira Brás, Sandra Tenreiro, Andreia M Silva, Tiago F Outeiro
Published in: FEMS Yeast Research, 18/8, 2018, ISSN 1567-1364
Publisher: FEMS Yeast Res
DOI: 10.1093/femsyr/foy108

Synucleinopathies: Where we are and where we need to go

Author(s): Inês Caldeira Brás, Antonio Dominguez‐Meijide, Ellen Gerhardt, David Koss, Diana F. Lázaro, Patrícia I. Santos, Eftychia Vasili, Mary Xylaki, Tiago Fleming Outeiro
Published in: Journal of Neurochemistry, 153/4, 2020, Page(s) 433-454, ISSN 0022-3042
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/jnc.14965

Mechanisms of alpha-synuclein toxicity: An update and outlook

Author(s): Inês Caldeira Brás, Mary Xylaki, Tiago Fleming Outeiro
Published in: Recent Advances in Parkinson's Disease, 252, 2020, Page(s) 91-129, ISBN 9780444642608
Publisher: Elsevier
DOI: 10.1016/bs.pbr.2019.10.005