Synaptic dysfunction in Neurodegenerative Diseases

Deliverables

Documents, reports (1)

Review of the ESR progress reports M54

M54 review of the ESR progress reports

Publications

Peer reviewed articles (9)

Contribution of the astrocytic tau pathology to synapse loss in progressive supranuclear palsy and corticobasal degeneration

Author(s): Nils Briel, Katrin Pratsch, Sigrun Roeber, Thomas Arzberger, Jochen Herms
Published in: Brain Pathology, 31/4, 2021, Page(s) e12914, ISSN 1015-6305
Publisher: International Society of Neuropathology
DOI: 10.1111/bpa.12914

VAMP4 Controls Constitutive Recycling and Sorting of Post-Synaptic Receptors in Neuronal Dendrites

Author(s): May Bakr, Damien Jullié, Julia Krapivkina, Lou Bouit, Jennifer Petersen, Natacha Retailleau, Christelle Breillat, Daniel Choquet, David Perrais
Published in: SSRN Electronic Journal, 2021, ISSN 1556-5068
Publisher: Cell Press
DOI: 10.2139/ssrn.3762644

The Links between ALS and NF-κB

Author(s): Emma Källstig, Brian D. McCabe, Bernard L. Schneider
Published in: International Journal of Molecular Sciences, 22/8, 2021, Page(s) 3875, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22083875

FRET-Based Screening Identifies p38 MAPK and PKC Inhibition as Targets for Prevention of Seeded α-Synuclein Aggregation

Author(s): Alexander Svanbergsson, Fredrik Ek, Isak Martinsson, Jordi Rodo, Di Liu, Edoardo Brandi, Caroline Haikal, Laura Torres-Garcia, Wen Li, Gunnar Gouras, Roger Olsson, Tomas Björklund, Jia-Yi Li
Published in: Neurotherapeutics, Online ahead of print, 2021, Page(s) not available, ISSN 1933-7213
Publisher: Elsevier BV
DOI: 10.1007/s13311-021-01070-1

Glycation in Huntington’s Disease: A Possible Modifier and Target for Intervention

Author(s): Inês Caldeira Brás, Annekatrin König, Tiago Fleming Outeiro
Published in: Journal of Huntington's Disease, 8/3, 2019, Page(s) 245-256, ISSN 1879-6397
Publisher: IOS Press
DOI: 10.3233/jhd-190366

Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies

Author(s): Inês C. Brás, Tiago F. Outeiro
Published in: Cells, 10/2, 2021, Page(s) 375, ISSN 2073-4409
Publisher: PMC
DOI: 10.3390/cells10020375

Sensing α-Synuclein From the Outside via the Prion Protein: Implications for Neurodegeneration

Author(s): Inês Caldeira Brás, Luísa V. Lopes, Tiago Fleming Outeiro
Published in: Movement Disorders, 33/11, 2018, Page(s) 1675-1684, ISSN 0885-3185
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/mds.27478

Identification of novel protein phosphatases as modifiers of alpha-synuclein aggregation in yeast

Author(s): Inês Caldeira Brás, Sandra Tenreiro, Andreia M Silva, Tiago F Outeiro
Published in: FEMS Yeast Research, 18/8, 2018, ISSN 1567-1364
Publisher: FEMS Yeast Res
DOI: 10.1093/femsyr/foy108

Synucleinopathies: Where we are and where we need to go

Author(s): Inês Caldeira Brás, Antonio Dominguez‐Meijide, Ellen Gerhardt, David Koss, Diana F. Lázaro, Patrícia I. Santos, Eftychia Vasili, Mary Xylaki, Tiago Fleming Outeiro
Published in: Journal of Neurochemistry, 153/4, 2020, Page(s) 433-454, ISSN 0022-3042
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/jnc.14965

Book chapters (1)

Mechanisms of alpha-synuclein toxicity: An update and outlook

Author(s): Inês Caldeira Brás, Mary Xylaki, Tiago Fleming Outeiro
Published in: Recent Advances in Parkinson's Disease, 252, 2020, Page(s) 91-129, ISBN 9780444642608
Publisher: Elsevier
DOI: 10.1016/bs.pbr.2019.10.005