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PROTECTion against Endocrine Disruptors; Detection, mixtures, health effects, risk assessment and communication.

Deliverables

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Publications

A mixture of persistent organic pollutants relevant for human exposure inhibits the transactivation activity of the aryl hydrocarbon receptor in vitro

Author(s): T.Q. Doan, H.F. Berntsen, S. Verhaegen, E. Ropstad, L. Connolly, A. Igout, M. Muller, M.L. Scippo
Published in: Environmental Pollution, Issue 254, 2019, Page(s) 113098, ISSN 0269-7491
DOI: 10.1016/j.envpol.2019.113098

Elucidating the aryl hydrocarbon receptor antagonism from a chemical-structural perspective


Published in: ISSN 1062-936X
DOI: 10.1080/1062936x.2019.1708460

Detection of high PBDD/Fs levels and dioxin-like activity in toys using a combination of GC-HRMS, rat-based and human-based DR CALUX® reporter gene assays

Author(s): Clémence Budin, Jindrich Petrlik, Jitka Strakova, Stephan Hamm, Bjorn Beeler, Peter Behnisch, Harrie Besselink, Bart van der Burg, Abraham Brouwer
Published in: Chemosphere, Issue 251, 2020, Page(s) 126579, ISSN 0045-6535
DOI: 10.1016/j.chemosphere.2020.126579

Potential adverse effects on animal health and performance caused by the addition of mineral adsorbents to feeds to reduce mycotoxin exposure

Author(s): Christopher T. Elliott, Lisa Connolly, Oluwatobi Kolawole
Published in: Mycotoxin Research, Issue 36/1, 2020, Page(s) 115-126, ISSN 0178-7888
DOI: 10.1007/s12550-019-00375-7

Comparative In Vitro Assessment of a Range of Commercial Feed Additives with Multiple Mycotoxin Binding Claims

Author(s): Kolawole, Meneely, Greer, Chevallier, Jones, Connolly, Elliott
Published in: Toxins, Issue 11/11, 2019, Page(s) 659, ISSN 2072-6651
DOI: 10.3390/toxins11110659

Human blood-based exposure levels of persistent organic pollutant (POP) mixtures antagonise androgen receptor transactivation and translocation

Author(s): J. McComb, I.G. Mills, M. Muller, H.F. Berntsen, K.E. Zimmer, E. Ropstad, S. Verhaegen, L. Connolly
Published in: Environment International, Issue 132, 2019, Page(s) 105083, ISSN 0160-4120
DOI: 10.1016/j.envint.2019.105083

DMSO effects larval zebrafish (Danio rerio) behavior, with additive and interaction effects when combined with positive controls

Author(s): Maria Christou, Arturas Kavaliauskis, Erik Ropstad, Thomas William Kenneth Fraser
Published in: Science of The Total Environment, Issue 709, 2020, Page(s) 134490, ISSN 0048-9697
DOI: 10.1016/j.scitotenv.2019.134490

Antagonistic activity towards the androgen receptor independent from natural sex hormones in human milk samples from the Norwegian HUMIS cohort

Author(s): Bérénice Collet, Barbara M.A. van Vugt-Lussenburg, Kees Swart, Rick Helmus, Matthijs Naderman, Eva de Rijke, Merete Eggesbø, Abraham Brouwer, Bart van der Burg
Published in: Environment International, Issue 143, 2020, Page(s) 105948, ISSN 0160-4120
DOI: 10.1016/j.envint.2020.105948

Calcium signaling as a possible mechanism behind increased locomotor response in zebrafish larvae exposed to a human relevant persistent organic pollutant mixture or PFOS

Author(s): Maria Christou, Thomas W.K. Fraser, Vidar Berg, Erik Ropstad, Jorke H. Kamstra
Published in: Environmental Research, Issue 187, 2020, Page(s) 109702, ISSN 0013-9351
DOI: 10.1016/j.envres.2020.109702

Acute Exposure to Zearalenone Disturbs Intestinal Homeostasis by Modulating the Wnt/β-Catenin Signaling Pathway

Author(s): Tarek Lahjouji, Aurora Bertaccini, Manon Neves, Sylvie Puel, Isabelle P. Oswald, Laura Soler
Published in: Toxins, Issue 12/2, 2020, Page(s) 113, ISSN 2072-6651
DOI: 10.3390/toxins12020113