Deliverables Documents, reports (8) Final WP6 report Final WP6 report. Completion of network-wide events Completion of network-wide events. End of Project Meeting/Final Report End of Project Meeting/Final Report. Final WP2 report Final WP2 report. Final WP5 report Final WP5 report. Final WP7 report Final WP7 report. Final WP3 report Final WP3 report. Final WP4 report Final WP4 report. Other (2) Completion of Dissemination and Outreach activities as outlined in section 2.3 and listed in Table 2.3a. Award Doctoral Degree (where appropriate) Award Doctoral Degrees (where appropriate). Websites, patent fillings, videos etc. (2) Web-site/intranet Web-site/intranet. Wikipedia entry Wikipedia entry. Publications Peer reviewed articles (32) Targeting the aryl hydrocarbon receptor with a novel set of triarylmethanes. Author(s): Elizabeth Goya-Jorge; Céline Rampal; Rafael Gozalbes; Maité Sylla-Iyarreta Veitía; Clotilde Ferroud; Nicolas Loones; Laureano E. Carpio; Rosa M. Giner; Stephen J. Barigye Published in: European Journal of Medicinal Chemistry, 2020, ISSN 0223-5234 Publisher: Elsevier BV DOI: 10.1016/j.ejmech.2020.112777 Public Awareness and Risk Perceptions of Endocrine Disrupting Chemicals: A Qualitative Study Author(s): Melissa Kelly, Lisa Connolly, Moira Dean Published in: International Journal of Environmental Research and Public Health, Issue 17/21, 2020, Page(s) 7778, ISSN 1660-4601 Publisher: MDPI DOI: 10.3390/ijerph17217778 Discovery of 2-aryl and 2-pyridinylbenzothiazoles endowed with antimicrobial and aryl hydrocarbon receptor agonistic activities Author(s): Elizabeth Goya-Jorge, Fatma Abdmouleh, Laureano E. Carpio, Rosa M. Giner, Maité Sylla-Iyarreta Veitía Published in: European Journal of Pharmaceutical Sciences, Issue 151, 2020, Page(s) 105386, ISSN 0928-0987 Publisher: Elsevier BV DOI: 10.1016/j.ejps.2020.105386 Plant Occurring Flavonoids as Modulators of the Aryl Hydrocarbon Receptor Author(s): Elizabeth Goya-Jorge, María Elisa Jorge Rodríguez, Maité Sylla-Iyarreta Veitía, Rosa M. Giner Published in: Molecules, Issue 26/8, 2021, Page(s) 2315, ISSN 1420-3049 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/molecules26082315 PROTECTion against Endocrine Disruption through Quantitative Structure-Activity Relationship modelling [“Revisión de los modelos computacionales que relacionan la estructura química con la disrupción del sistema endocrino”] Author(s): Elizabeth Goya-Jorge Jesús V. de Julián-Ortiz Rafael Gozalbes Published in: Revista de Toxicología, Issue June 2020, 2020, Page(s) 55-68, ISSN 0212-7113 Publisher: Asociacion Espanola de Toxicologia Human-Based Exposure Levels of Perfluoroalkyl Acids May Induce Harmful Effects to Health by Disrupting Major Components of Androgen Receptor Signalling In Vitro Author(s): J. McComb, I. G. Mills, Hanne Friis Berntsen, E. Ropstad, S. Verhaegen, L. Connolly Published in: Exposure and Health, Issue 12/3, 2020, Page(s) 527-538, ISSN 2451-9766 Publisher: Springer DOI: 10.1007/s12403-019-00318-8 Induction of AhR transactivation by PBDD/Fs and PCDD/Fs using a novel human-relevant, high-throughput DRhuman CALUX reporter gene assay Author(s): Clémence Budin, Harrie Besselink, Barbara M.A. van Vugt-Lussenburg, Hai-Yen Man, Bart van der Burg, Abraham Brouwer Published in: Chemosphere, Issue 263, 2021, Page(s) 128086, ISSN 0045-6535 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.chemosphere.2020.128086 A human relevant mixture of persistent organic pollutants (POPs) and perfluorooctane sulfonic acid (PFOS) enhance nerve growth factor (NGF)-induced neurite outgrowth in PC12 cells Author(s): Ajay Yadav, Mazia Amber, Denis Zosen, Nils Anders Labba, Eva Henriette Willemijn Huiberts, Johanna Samulin Erdem, Fred Haugen, Hanne Friis Berntsen, Shanbeh Zienolddiny, Ragnhild Elisabeth Paulsen, Erik Ropstad, Lisa Connolly, Steven Verhaegen Published in: Toxicology Letters, Issue 338, 2021, Page(s) 85-96, ISSN 0378-4274 Publisher: Elsevier BV DOI: 10.1016/j.toxlet.2020.12.007 Investigation of In Vitro Endocrine Activities of Microcystis and Planktothrix Cyanobacterial Strains Author(s): Vittoria Mallia, Lada Ivanova, Gunnar S. Eriksen, Emma Harper, Lisa Connolly, Silvio Uhlig Published in: Toxins, Issue 12/4, 2020, Page(s) 228, ISSN 2072-6651 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/toxins12040228 Effects of Defined Mixtures of Persistent Organic Pollutants (POPs) on Pre-lethal Cytotoxicity in the Human A-498 Kidney Cell Line In Vitro Author(s): Mazia Amber, Yuling Xie, Hanne Friis Berntsen, Karin Elizabeth Zimmer, Erik Ropstad, Steven Verhaegen, Lisa Connolly Published in: Exposure and Health, 2021, ISSN 2451-9766 Publisher: Springer nature DOI: 10.1007/s12403-021-00396-7 In vitro profiling of the potential endocrine disrupting activities affecting steroid and aryl hydrocarbon receptors of compounds and mixtures prevalent in human drinking water resources Author(s): Doan TQ, Connolly L, Igout A, Nott K, Muller M, Scippo ML Published in: Chemosphere, Issue 258, 2020, Page(s) 127332, ISSN 0045-6535 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.chemosphere.2020.127332 Predictive modeling of aryl hydrocarbon receptor (AhR) agonism Author(s): Elizabeth Goya-Jorge, Rosa M. Giner, Maité Sylla-Iyarreta Veitía, Rafael Gozalbes, Stephen J. Barigye Published in: Chemosphere, Issue 256, 2020, Page(s) 127068, ISSN 0045-6535 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.chemosphere.2020.127068 Assessing the chemical-induced estrogenicity using in silico and in vitro methods Author(s): Elizabeth Goya-Jorge, Mazia Amber, Rafael Gozalbes, Lisa Connolly, Stephen J. Barigye Published in: Environmental Toxicology and Pharmacology, 2021, Page(s) 103688, ISSN 1382-6689 Publisher: Elsevier BV DOI: 10.1016/j.etap.2021.103688 Versicolorin A enhances the genotoxicity of aflatoxin B1 in human liver cells by inducing the transactivation of the Ah-receptor Author(s): Clémence Budin, Hai-Yen Man, Carine Al-Ayoubi, Sylvie Puel, Barbara M.A. van Vugt-Lussenburg, Abraham Brouwer, Isabelle P. Oswald, Bart van der Burg, Laura Soler Published in: Food and Chemical Toxicology, Issue 153, 2021, Page(s) 112258, ISSN 0278-6915 Publisher: Elsevier BV DOI: 10.1016/j.fct.2021.112258 The insulin-like growth factor system: A target for endocrine disruptors? Author(s): Chiara Talia, Lisa Connolly, Paul A. Fowler Published in: Environment International, Issue 147, 2021, Page(s) 106311, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2020.106311 Testing the twin testosterone transfer hypothesis—intergenerational analysis of 317 dizygotic twins born in Aberdeen, Scotland Author(s): Chiara Talia, Edwin-Amalraj Raja, Sohinee Bhattacharya, Paul A Fowler Published in: Human Reproduction, Issue 35/7, 2020, Page(s) 1702-1711, ISSN 0268-1161 Publisher: Oxford University Press DOI: 10.1093/humrep/deaa091 Microcystins and Microcystis aeruginosa PCC7806 extracts modulate steroidogenesis differentially in the human H295R adrenal model Author(s): Vittoria Mallia, Steven Verhaegen, Bjarne Styrishave, Gunnar Sundstøl Eriksen, Malene Louise Johannsen, Erik Ropstad, Silvio Uhlig Published in: PLOS ONE, Issue 15/12, 2020, Page(s) e0244000, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0244000 A mixture of persistent organic pollutants relevant for human exposure inhibits the transactivation activity of the aryl hydrocarbon receptor in vitro Author(s): T.Q. Doan, H.F. Berntsen, S. Verhaegen, E. Ropstad, L. Connolly, A. Igout, M. Muller, M.L. Scippo Published in: Environmental Pollution, Issue 254, 2019, Page(s) 113098, ISSN 0269-7491 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envpol.2019.113098 Elucidating the aryl hydrocarbon receptor antagonism from a chemical-structural perspective Author(s): E. Goya-Jorge, T.Q. Doan, M.L. Scippo, M. Muller, R.M. Giner, S.J. Barigye, R. Gozalbes Published in: SAR and QSAR in Environmental Research, Issue 31/3, 2020, Page(s) 209-226, ISSN 1062-936X Publisher: Taylor & Francis DOI: 10.1080/1062936x.2019.1708460 Detection of high PBDD/Fs levels and dioxin-like activity in toys using a combination of GC-HRMS, rat-based and human-based DR CALUX® reporter gene assays Author(s): Clémence Budin, Jindrich Petrlik, Jitka Strakova, Stephan Hamm, Bjorn Beeler, Peter Behnisch, Harrie Besselink, Bart van der Burg, Abraham Brouwer Published in: Chemosphere, Issue 251, 2020, Page(s) 126579, ISSN 0045-6535 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.chemosphere.2020.126579 Potential adverse effects on animal health and performance caused by the addition of mineral adsorbents to feeds to reduce mycotoxin exposure Author(s): Christopher T. Elliott, Lisa Connolly, Oluwatobi Kolawole Published in: Mycotoxin Research, Issue 36/1, 2020, Page(s) 115-126, ISSN 0178-7888 Publisher: Hans W. Schmidt DOI: 10.1007/s12550-019-00375-7 Comparative In Vitro Assessment of a Range of Commercial Feed Additives with Multiple Mycotoxin Binding Claims Author(s): Kolawole, Meneely, Greer, Chevallier, Jones, Connolly, Elliott Published in: Toxins, Issue 11/11, 2019, Page(s) 659, ISSN 2072-6651 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/toxins11110659 Human blood-based exposure levels of persistent organic pollutant (POP) mixtures antagonise androgen receptor transactivation and translocation Author(s): J. McComb, I.G. Mills, M. Muller, H.F. Berntsen, K.E. Zimmer, E. Ropstad, S. Verhaegen, L. Connolly Published in: Environment International, Issue 132, 2019, Page(s) 105083, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2019.105083 DMSO effects larval zebrafish (Danio rerio) behavior, with additive and interaction effects when combined with positive controls Author(s): Maria Christou, Arturas Kavaliauskis, Erik Ropstad, Thomas William Kenneth Fraser Published in: Science of The Total Environment, Issue 709, 2020, Page(s) 134490, ISSN 0048-9697 Publisher: Elsevier BV DOI: 10.1016/j.scitotenv.2019.134490 Antagonistic activity towards the androgen receptor independent from natural sex hormones in human milk samples from the Norwegian HUMIS cohort Author(s): Bérénice Collet, Barbara M.A. van Vugt-Lussenburg, Kees Swart, Rick Helmus, Matthijs Naderman, Eva de Rijke, Merete Eggesbø, Abraham Brouwer, Bart van der Burg Published in: Environment International, Issue 143, 2020, Page(s) 105948, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2020.105948 Calcium signaling as a possible mechanism behind increased locomotor response in zebrafish larvae exposed to a human relevant persistent organic pollutant mixture or PFOS Author(s): Maria Christou, Thomas W.K. Fraser, Vidar Berg, Erik Ropstad, Jorke H. Kamstra Published in: Environmental Research, Issue 187, 2020, Page(s) 109702, ISSN 0013-9351 Publisher: Academic Press DOI: 10.1016/j.envres.2020.109702 Acute Exposure to Zearalenone Disturbs Intestinal Homeostasis by Modulating the Wnt/β-Catenin Signaling Pathway Author(s): Tarek Lahjouji, Aurora Bertaccini, Manon Neves, Sylvie Puel, Isabelle P. Oswald, Laura Soler Published in: Toxins, Issue 12/2, 2020, Page(s) 113, ISSN 2072-6651 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/toxins12020113 Novel Microcystins from Planktothrix prolifica NIVA-CYA 544 Identified by LC-MS/MS, Functional Group Derivatization and 15N-labeling Author(s): Vittoria Mallia, Silvio Uhlig, Cheryl Rafuse, Juris Meija, Christopher O. Miles Published in: Marine Drugs, Issue 17/11, 2019, Page(s) 643, ISSN 1660-3397 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/md17110643 A human relevant mixture of persistent organic pollutants (POPs) and perfluorooctane sulfonic acid (PFOS) differentially affect glutamate induced excitotoxic responses in chicken cerebellum granule neurons (CGNs) in vitro Author(s): Ajay Yadav, Steven Verhaegen, Evelien Verbruggen, Marie Kerhoas, Eva Henriëtte Willemijn Huiberts, Mussie Ghezu Hadera, Hanne Friis Berntsen, Karin Elisabeth Zimmer, Erik Ropstad, Ragnhild Elisabeth Paulsen Published in: Reproductive Toxicology, Issue 100, 2021, Page(s) 109-119, ISSN 0890-6238 Publisher: Elsevier BV DOI: 10.1016/j.reprotox.2021.01.008 Developmental exposure to a POPs mixture or PFOS increased body weight and reduced swimming ability but had no effect on reproduction or behavior in zebrafish adults Author(s): Maria Christou, Erik Ropstad, Stephen Brown, Jorke H. Kamstra, Thomas W.K. Fraser Published in: Aquatic Toxicology, Issue 237, 2021, Page(s) 105882, ISSN 0166-445X Publisher: Elsevier BV DOI: 10.1016/j.aquatox.2021.105882 Low Doses of Mycotoxin Mixtures below EU Regulatory Limits Can Negatively Affect the Performance of Broiler Chickens: A Longitudinal Study Author(s): Oluwatobi Kolawole, Abigail Graham, Caroline Donaldson, Bronagh Owens, Wilfred A. Abia, Julie Meneely, Michael J. Alcorn, Lisa Connolly, Christopher T. Elliott Published in: Toxins, Issue 12/7, 2020, Page(s) 433, ISSN 2072-6651 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/toxins12070433 In vitro differential responses of rat and human aryl hydrocarbon receptor to two distinct ligands and to different polyphenols. Author(s): Marc Muller; Ahmed Igout; Thi-Que Doan; Lisa Connolly; Marie-Louise Scippo Published in: Environmental Pollution, Issue 6, 2020, ISSN 0269-7491 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envpol.2020.114966 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
