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Decoding dynamic chromatin signaling by single-molecule multiplex detection

Publications

BAF restricts cGAS on nuclear DNA to prevent innate immune activation

Author(s): Guey B, Wischnewski M, Decout A, Makasheva K, Kaynak M, Sakar MS, Fierz B, Ablasser A
Published in: Science, 2020, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aaw6421

Structural mechanism of cGAS inhibition by the nucleosome

Author(s): Pathare GR, Decout A, Glück S, Cavadini S, Makasheva K, Hovius R, Kempf G, Weiss J, Kozicka Z, Guey B, Melenec P, Fierz B, Thomä NH, Ablasser A.
Published in: Nature, 2020, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-020-2750-6

Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α

Author(s): Sinan Kilic, Suren Felekyan, Olga Doroshenko, Iuliia Boichenko, Mykola Dimura, Hayk Vardanyan, Louise C. Bryan, Gaurav Arya, Claus A. M. Seidel, Beat Fierz
Published in: Nature Communications, 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-017-02619-5

A bi-terminal protein ligation strategy to probe chromatin structure during DNA damage

Author(s): Sinan Kilic, Iuliia Boichenko, Carolin C. Lechner, Beat Fierz
Published in: Chemical Science, 9/15, 2018, Page(s) 3704-3709, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8sc00681d

Chromatin Fiber Invasion and Nucleosome Displacement by the Rap1 Transcription Factor

Author(s): Maxime Mivelaz, Anne-Marinette Cao, Slawomir Kubik, Sevil Zencir, Ruud Hovius, Iuliia Boichenko, Anna Maria Stachowicz, Christoph F. Kurat, David Shore, Beat Fierz
Published in: Molecular Cell, 2019, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.10.025

Multiplexed Single-Molecule Experiments Reveal Nucleosome Invasion Dynamics of the Cas9 Genome Editor

Author(s): Makasheva K, Bryan LC, Anders C, Panikulam S, Jinek M, Fierz B
Published in: JACS, 2021, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.1c06195

Chemical and biophysical methods to explore dynamic mechanisms of chromatin silencing

Author(s): Iuliia Boichenko, Beat Fierz
Published in: Current Opinion in Chemical Biology, 51, 2019, Page(s) 1-10, ISSN 1367-5931
Publisher: Elsevier BV
DOI: 10.1016/j.cbpa.2019.01.022

Datasets

A Bi-Terminal Protein Ligation Strategy To Probe Chromatin Structure During Dna Damage - Fig. 4F

Author(s): Kilic, Sinan; Boichenko, Iuliia; Lechner, Carolin C.; Fierz, Beat
Published in: Zenodo

Chromatin fiber invasion and nucleosome displacement by the Rap1 transcription factor_Figure5f_1

Author(s): Mivelaz, Maxime; Cao, Anne-Marinette; Kubik, Slawomir; Zencir, Sevil; Hovius, Ruud; Boichenko, Iuliia; Stachowicz, Anna Maria; Kurat, Christoph F.; Shore, David; Fierz, Beat
Published in: Zenodo

Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α-Fig. 2def

Author(s): Kilic, Sinan; Felekyan, Suren; Doroshenko, Olga; Boichenko, Iuliia; Dimura, Mykola; Vardanyan, Hayk; Bryan, Louise C.; Arya, Gaurav; Seidel, Claus A.M.; Fierz, Beat
Published in: Zenodo

Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α-Fig. 7cde

Author(s): Kilic, Sinan; Felekyan, Suren; Doroshenko, Olga; Boichenko, Iuliia; Dimura, Mykola; Vardanyan, Hayk; Bryan, Louise C.; Arya, Gaurav; Seidel, Claus.A.M.; Fierz, Beat
Published in: Zenodo

Chromatin fiber invasion and nucleosome displacement by the Rap1 transcription factor_FigureS6

Author(s): Mivelaz, Maxime; Cao, Anne-Marinette; Kubik, Slawomir; Zencir, Sevil; Hovius, Ruud; Boichenko, Iuliia; Stachowicz, Anna Maria; Kurat, Christoph F.; Shore, David; Fierz, Beat
Published in: Zenodo

Chromatin fiber invasion and nucleosome displacement by the Rap1 transcription factor_Figure5f_2

Author(s): Mivelaz, Maxime; Cao, Anne-Marinette; Kubik, Slawomir; Zencir, Sevil; Hovius, Ruud; Boichenko, Iuliia; Stachowicz, Anna Maria; Kurat, Christoph F.; Shore, David; Fierz, Beat
Published in: Zenodo

Chromatin fiber invasion and nucleosome displacement by the Rap1 transcription factor_Fig.2,3,S3,S4,S7

Author(s): Mivelaz, Maxime; Cao, Anne-Marinette; Kubik, Slawomir; Zencir, Sevil; Hovius, Ruud; Boichenko, Iuliia; Stachowicz, Anna Maria; Kurat, Christoph F.; Shore, David; Fierz, Beat
Published in: Zenodo

Single-Molecule Fret Reveals Multiscale Chromatin Dynamics Modulated By Hp1Α-Fig. 1Df

Author(s): Kilic, Sinan; Felekyan, Suren; Doroshenko, Olga; Boichenko, Iuliia; Dimura, Mykola; Vardanyan, Hayk; Bryan, Louise C.; Arya, Gaurav; Seidel, Claus.A.M.; Fierz, Beat
Published in: Zenodo

Chromatin fiber invasion and nucleosome displacement by the Rap1 transcription factor_Figure5e_1

Author(s): Mivelaz, Maxime; Cao, Anne-Marinette; Kubik, Slawomir; Zencir, Sevil; Hovius, Ruud; Boichenko, Iuliia; Stachowicz, Anna Maria; Kurat, Christoph F.; Shore, David; Fierz, Beat
Published in: Zenodo

A bi-terminal protein ligation strategy to probe chromatin structure during DNA damage - Fig. 4e

Author(s): Kilic, Sinan; Boichenko, Iuliia; Lechner, Carolin C.; Fierz, Beat
Published in: Zenodo

A Bi-Terminal Protein Ligation Strategy To Probe Chromatin Structure During Dna Damage - Fig. 4D

Author(s): Kilic, Sinan; Boichenko, Iuliia; Lechner, Carolin C.; Beat Fierz
Published in: Zenodo

Chromatin fiber invasion and nucleosome displacement by the Rap1 transcription factor_Figure5e_2

Author(s): Mivelaz, Maxime; Cao, Anne-Marinette; Kubik, Slawomir; Zencir, Sevil; Hovius, Ruud; Boichenko, Iuliia; Stachowicz, Anna Maria; Kurat, Christoph F.; Shore, David; Fierz, Beat
Published in: Zenodo