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Ribosome inhibition by nascent or antimicrobial peptides

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The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome

Author(s): Mario Mardirossian, Natacha Pérébaskine, Monica Benincasa, Stefano Gambato, Sven Hofmann, Paul Huter, Claudia Müller, Kai Hilpert, C. Axel Innis, Alessandro Tossi, Daniel N. Wilson
Published in: Cell Chemical Biology, Issue 25/5, 2018, Page(s) 530-539.e7, ISSN 2451-9456
DOI: 10.1016/j.chembiol.2018.02.004

Ribosomal stalling landscapes revealed by high-throughput inverse toeprinting of mRNA libraries

Author(s): Britta Seip, Guénaël Sacheau, Denis Dupuy, C Axel Innis
Published in: Life Science Alliance, Issue 1/5, 2018, Page(s) e201800148, ISSN 2575-1077
DOI: 10.26508/lsa.201800148

Ornithine capture by a translating ribosome controls bacterial polyamine synthesis

Author(s): Alba Herrero del Valle, Britta Seip, Iñaki Cervera-Marzal, Guénaël Sacheau, A. Carolin Seefeldt, C. Axel Innis
Published in: Nature Microbiology, Issue 5/4, 2020, Page(s) 554-561, ISSN 2058-5276
DOI: 10.1038/s41564-020-0669-1

Proline-Rich Antimicrobial Peptides in Medicinal Maggots of Lucilia sericata Interact With Bacterial DnaK But Do Not Inhibit Protein Synthesis

Author(s): Małgorzata Cytryńska, Mohammad Rahnamaeian, Agnieszka Zdybicka-Barabas, Kristin Dobslaff, Thole Züchner, Guénaël Sacheau, C. Axel Innis, Andreas Vilcinskas
Published in: Frontiers in Pharmacology, Issue 11, 2020, ISSN 1663-9812
DOI: 10.3389/fphar.2020.00532

Using the Bacterial Ribosome as a Discovery Platform for Peptide-Based Antibiotics

Author(s): Justine Charon, Aitor Manteca, C. Axel Innis
Published in: Biochemistry, Issue 58/2, 2018, Page(s) 75-84, ISSN 0006-2960
DOI: 10.1021/acs.biochem.8b00927