The birth of protein complexes

Project Information

ComplexAssembly

Grant agreement ID: 724349

DOI 10.3030/724349

Project closed

EC signature date 3 February 2017

Start date 1 February 2018

End date 31 January 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 957 717,00

EU contribution € 1 957 717,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

Publications

Peer reviewed articles (11)

Benchmarking tomographic acquisition schemes for high-resolution structural biology

Author(s): Beata Turoňová, Wim J. H. Hagen, Martin Obr, Shyamal Mosalaganti, J. Wouter Beugelink, Christian E. Zimmerli, Hans-Georg Kräusslich, Martin Beck
Published in: Nature Communications, Issue 11/1, 2020, Page(s) 876, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-14535-2

The Benefits of Cotranslational Assembly: A Structural Perspective

Author(s): Andre Schwarz, Martin Beck
Published in: Trends in Cell Biology, Issue 29/10, 2019, Page(s) 791-803, ISSN 0962-8924
Publisher: Elsevier BV
DOI: 10.1016/j.tcb.2019.07.006

Pervasive Protein Thermal Stability Variation during the Cell Cycle

Author(s): Isabelle Becher, Amparo Andrés-Pons, Natalie Romanov, Frank Stein, Maike Schramm, Florence Baudin, Dominic Helm, Nils Kurzawa, André Mateus, Marie-Therese Mackmull, Athanasios Typas, Christoph W. Müller, Peer Bork, Martin Beck, Mikhail M. Savitski
Published in: Cell, Issue 173/6, 2018, Page(s) 1495-1507.e18, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2018.03.053

In situ architecture of the algal nuclear pore complex

Author(s): Shyamal Mosalaganti, Jan Kosinski, Sahradha Albert, Miroslava Schaffer, Daniela Strenkert, Patrice A. Salomé, Sabeeha S. Merchant, Jürgen M. Plitzko, Wolfgang Baumeister, Benjamin D. Engel, Martin Beck
Published in: Nature Communications, Issue 9/1, 2018, Page(s) 1-8, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-04739-y

Structure and Assembly of the Nuclear Pore Complex

Author(s): Bernhard Hampoelz, Amparo Andres-Pons, Panagiotis Kastritis, Martin Beck
Published in: Annual Review of Biophysics, Issue 48/1, 2019, Page(s) 515-536, ISSN 1936-122X
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-biophys-052118-115308

Co-translational assembly orchestrates competing biogenesis pathways

Author(s): Maximilian Seidel, Anja Becker, Filipa Pereira, Jonathan J. M. Landry, Nayara Trevisan Doimo de Azevedo, Claudia M. Fusco, Eva Kaindl, Natalie Romanov, Janina Baumbach, Julian D. Langer, Erin M. Schuman, Kiran Raosaheb Patil, Gerhard Hummer, Vladimir Benes, Martin Beck 
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-28878-5

Nuclear envelope assembly and dynamics during development

Author(s): Bernhard Hampoelz; Janina Baumbach
Published in: Seminars in Cell & Developmental Biology, Issue 1, 2022, Page(s) n/a - in press, ISSN 1084-9521
Publisher: Academic Press
DOI: 10.1016/j.semcdb.2022.02.028

AI-based structure prediction empowers integrative structural analysis of human nuclear pores

Author(s): Shyamal Mosalaganti, Agnieszka Obarska-Kosinska, Marc Siggel, Reiya Taniguchi, Beata Turonová, Christian E. Zimmerli, Katarzyna Buczak, Florian H. Schmidt, Erica Margiotta, Marie-Therese Mackmull, Wim J. H. Hagen, Gerhard Hummer, Jan Kosinski, Martin Beck
Published in: Science, 2022, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abm9506

Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis

Author(s): Bernhard Hampoelz, Andre Schwarz, Paolo Ronchi, Helena Bragulat-Teixidor, Christian Tischer, Imre Gaspar, Anne Ephrussi, Yannick Schwab, Martin Beck
Published in: Cell, Issue 179/3, 2019, Page(s) 671-686.e17, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2019.09.022

In-cell architecture of the nuclear pore and snapshots of its turnover.

Author(s): Matteo Allegretti; Christian E. Zimmerli; Vasileios Rantos; Florian Wilfling; Paolo Ronchi; Herman K.H. Fung; Chia-Wei Lee; Wim J. H. Hagen; Beata Turoňová; Kai Karius; Mandy Börmel; Xiaojie Zhang; Christoph W. Müller; Yannick Schwab; Julia Mahamid; Boris Pfander; Jan Kosinski; Martin Beck
Published in: Nature, Issue 3, 2020, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-020-2670-5

Nuclear pores dilate and constrict in cellulo

Author(s): Christian E. Zimmerli, Matteo Allegretti, Vasileios Rantos, Sara K. Goetz, Agnieszka Obarska-Kosinska, Ievgeniia Zagoriy, Aliaksandr Halavatyi, Gerhard Hummer, Julia Mahamid, Jan Kosinski, Martin Beck
Published in: Science, 2021, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abd9776

Other (1)

Co-translational binding of importins to nascent proteins

Author(s): Maximilian Seidel, Natalie Romanov, Agnieszka Obarska-Kosinska, Anja Becker, Nayara Trevisan Doimo de Azevedo, Jan Provaznik, Sankarshana R. Nagaraja, Jonathan J. M. Landry, View ORCID ProfileVladimir Benes, Martin Beck
Published in: bioRxiv, 2022
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.11.02.514836