Pushing the frontiers of biological imaging with genetically encoded fluorescence switches

Publications

An expanded palette of fluorogenic HaloTag probes with enhanced contrast for targeted cellular imaging

Author(s): Sylvestre P. J. T. Bachollet, Yuriy Shpinov, Fanny Broch, Hela Benaissa, Arnaud Gautier, Nicolas Pietrancosta, Jean-Maurice Mallet and Blaise Dumat
Published in: Organic and Biomolecular Chemistry, 2022, ISSN 1477-0539
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1ob02394b

Illuminating Cellular Biochemistry: Fluorogenic Chemogenetic Biosensors for Biological Imaging

Author(s): Fanny Broch, Arnaud Gautier
Published in: ChemPlusChem, Issue 85/7, 2020, Page(s) 1487-1497, ISSN 2192-6506
Publisher: Wiley-VCH Verlag
DOI: 10.1002/cplu.202000413

Fluorescence-Activating and Absorption-Shifting Tags for Advanced Imaging and Biosensing

Author(s): Arnaud Gautier
Published in: Accounts of Chemical Research, 2023, ISSN 1520-4898
Publisher: Accounts of Chemical Research
DOI: 10.1021/acs.accounts.2c00098

A fluorescent reporter system for anaerobic thermophiles

Author(s): Rémi Hocq, Sara Bottone, Arnaud Gautier, Stefan Pfügl
Published in: Frontiers in Bioengineering and Biotechnology, Issue 11, 2023, ISSN 2296-4185
Publisher: Frontiers Media INS
DOI: 10.3389/fbioe.2023.1226889

Engineering of Tunable Allosteric-like Fluorogenic Protein Sensors

Author(s): Fanny Broch, Lina El Hajji, Nicolas Pietrancosta, Arnaud Gautier
Published in: ACS Sensors, 2023, ISSN 2379-3694
Publisher: ACS publications
DOI: 10.1021/acssensors.3c01536

A Far‐Red Emitting Fluorescent Chemogenetic Reporter for In Vivo Molecular Imaging

Author(s): Chenge Li, Alison G. Tebo, Marion Thauvin, Marie‐Aude Plamont, Michel Volovitch, Xavier Morin, Sophie Vriz, Arnaud Gautier
Published in: Angewandte Chemie, Issue 132/41, 2020, Page(s) 18073-18079, ISSN 0044-8249
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ange.202006576

Visualizing the dynamics of exported bacterial proteins with the chemogenetic fluorescent reporter FAST

Author(s): Yankel Chekli, Caroline Peron-Cane, Dario Dell’Arciprete, Jean-François Allemand, Chenge Li, Jean-Marc Ghigo, Arnaud Gautier, Alice Lebreton, Nicolas Desprat, Christophe Beloin
Published in: Scientific Reports, Issue 10, 2020, Page(s) 15791, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-72498-2

Improved Chemical-Genetic Fluorescent Markers for Live Cell Microscopy

Author(s): Alison G. Tebo, Frederico M. Pimenta, Yu Zhang, Arnaud Gautier
Published in: Biochemistry, Issue 57/39, 2018, Page(s) 5648-5653, ISSN 0006-2960
Publisher: American Chemical Society
DOI: 10.1021/acs.biochem.8b00649

Fluorogenic Probing of Membrane Protein Trafficking

Author(s): Chenge Li, Aurélien Mourton, Marie-Aude Plamont, Vanessa Rodrigues, Isabelle Aujard, Michel Volovitch, Thomas Le Saux, Franck Perez, Sophie Vriz, Ludovic Jullien, Alain Joliot, Arnaud Gautier
Published in: Bioconjugate Chemistry, Issue 29/6, 2018, Page(s) 1823-1828, ISSN 1043-1802
Publisher: American Chemical Society
DOI: 10.1021/acs.bioconjchem.8b00180〉

Fluorogenic Protein-Based Strategies for Detection, Actuation, and Sensing

Author(s): Arnaud Gautier, Alison G. Tebo
Published in: BioEssays, Issue 40/10, 2018, Page(s) 1800118, ISSN 0265-9247
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/bies.201800118

Fluorogenic Labeling Strategies for Biological Imaging

Author(s): Chenge Li, Alison Tebo, Arnaud Gautier
Published in: International Journal of Molecular Sciences, Issue 18/7, 2017, Page(s) 1473, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms18071473〉

Circularly Permuted Fluorogenic Proteins for the Design of Modular Biosensors

Author(s): Alison G. Tebo, Frederico M. Pimenta, Martha Zoumpoulaki, Carlos Kikuti, Helena Sirkia, Marie-Aude Plamont, Anne Houdusse, Arnaud Gautier
Published in: ACS Chemical Biology, Issue 13/9, 2018, Page(s) 2392-2397, ISSN 1554-8929
Publisher: American Chemical Society
DOI: 10.1021/acschembio.8b00417

Next-Generation Fluorogen-Based Reporters and Biosensors for Advanced Bioimaging

Author(s): Tiphaine Péresse, Arnaud Gautier
Published in: International Journal of Molecular Sciences, Issue 20/24, 2019, Page(s) 6142, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20246142

A split fluorescent reporter with rapid and reversible complementation

Author(s): Alison G. Tebo, Arnaud Gautier
Published in: Nature Communications, Issue 10/1, 2019, Page(s) 2822, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-10855-0

A fluorogenic chemically induced dimerization technology for controlling, imaging and sensing protein proximity

Author(s): Sara Bottone, Octave Joliot, Zeyneb Vildan Cakil, Lina El Hajji, Louise-Marie Rakotoarison, Gaelle Boncompain, Franck Perez & Arnaud Gautier
Published in: Nature Methods, 2023, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-023-01988-8

Engineering of a fluorescent chemogenetic reporter with tunable color for advanced live-cell imaging

Author(s): Hela Benaissa, Karim Ounoughi, Isabelle Aujard, Evelyne Fischer, Rosette Goïame, Julie Nguyen, Alison G. Tebo, Chenge Li, Thomas Le Saux, Giulia Bertolin, Marc Tramier, Lydia Danglot, Nicolas Pietrancosta, Xavier Morin, Ludovic Jullien, Arnaud Gautier
Published in: Nature Communications, Issue 12, 2021, Page(s) 6989, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-27334-0

Engineering Glowing Chemogenetic Hybrids for Spying on Cells

Author(s): Hela Ben Aissa, Arnaud Gautier
Published in: European Journal of Organic Chemistry, Issue 2020/35, 2020, Page(s) 5637-5646, ISSN 1434-193X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.202000340

Orthogonal fluorescent chemogenetic reporters for multicolor imaging

Author(s): Alison G. Tebo, Benjamien Moeyaert, Marion Thauvin, Irene Carlon-Andres, Dorothea Böken, Michel Volovitch, Sergi Padilla-Parra, Peter Dedecker, Sophie Vriz, Arnaud Gautier
Published in: Nature Chemical Biology, Issue 17, 2021, Page(s) 30-38, ISSN 1552-4469
Publisher: Nature Publishing group
DOI: 10.1038/s41589-020-0611-0

Sensing cellular biochemistry with fluorescent chemical–genetic hybrids

Author(s): Arnaud Gautier, Alison G. Tebo
Published in: Current Opinion in Chemical Biology, Issue 57, 2020, Page(s) 58-64, ISSN 1367-5931
Publisher: Elsevier BV
DOI: 10.1016/j.cbpa.2020.04.005

Genetic Targeting of Solvatochromic Dyes for Probing Nanoscale Environments of Proteins in Organelles

Author(s): Rémi Pelletier, Dmytro I. Danylchuk, Hela Benaissa, Fanny Broch, Romain Vauchelles, Arnaud Gautier, Andrey Klymchenko
Published in: Analytical Chemistry, 2023, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.3c00515

CHAPTER 3. The Glowing Panoply of Fluorogen-based Markers for Advanced Bioimaging

Author(s): Arnaud Gautier
Published in: Optogenetics - Light-driven Actuators and Light-emitting Sensors in Cell Biology, 2018, Page(s) 41-62, ISBN 978-1-78801-237-9
Publisher: Royal Society of Chemistry
DOI: 10.1039/9781788013284-00041

Isolating and Engineering Fluorescence-Activating Proteins Using Yeast Surface Display

Author(s): Lina El Hajji, Hela Benaissa, Arnaud Gautier
Published in: Yeast Surface Display, Methods in Molecular Biology, Issue 2491, 2022, Page(s) 593-626, ISBN 978-1-0716-2284-1
Publisher: Humana
DOI: 10.1007/978-1-0716-2285-8_25

Intellectual Property Rights

MEMBRANE-IMPERMEANT FLUOROGENIC CHROMOPHORES

Application/Publication number: 17 305591
Date: 2017-05-19

SPLIT PHOTOACTIVE YELLOW PROTEIN COMPLEMENTATION SYSTEM AND USES THEREOF

Application/Publication number: 20 20059635
Date: 2020-04-03