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Epigenomic Reprogramming of Adipose Tissue Function and Energy Metabolism in Type 2 Diabetes

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GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation

Author(s): Karima Drareni, Raphaëlle Ballaire, Serena Barilla, Mano J. Mathew, Amine Toubal, Rongrong Fan, Ning Liang, Catherine Chollet, Zhiqiang Huang, Maria Kondili, Fabienne Foufelle, Antoine Soprani, Ronan Roussel, Jean-François Gautier, Fawaz Alzaid, Eckardt Treuter, Nicolas Venteclef
Published in: Cell Reports, Issue 24/11, 2018, Page(s) 2957-2971.e6, ISSN 2211-1247
DOI: 10.1016/j.celrep.2018.08.032

Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health

Author(s): Ludivine Laurans, Nicolas Venteclef, Yacine Haddad, Mouna Chajadine, Fawaz Alzaid, Sarvenaz Metghalchi, Bruno Sovran, Raphael G. P. Denis, Julien Dairou, Marina Cardellini, Jose-Maria Moreno-Navarrete, Marjolene Straub, Sarah Jegou, Claire McQuitty, Thomas Viel, Bruno Esposito, Bertrand Tavitian, Jacques Callebert, Serge H. Luquet, Massimo Federici, José Manuel Fernandez-Real, Remy Burcelin, Jean
Published in: Nature Medicine, Issue 24/8, 2018, Page(s) 1113-1120, ISSN 1078-8956
DOI: 10.1038/s41591-018-0060-4

Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance

Author(s): Jérôme Gilleron, Gwennaëlle Bouget, Stoyan Ivanov, Cindy Meziat, Franck Ceppo, Bastien Vergoni, Mansour Djedaini, Antoine Soprani, Karine Dumas, Arnaud Jacquel, Laurent Yvan-Charvet, Nicolas Venteclef, Jean-François Tanti, Mireille Cormont
Published in: Cell Reports, Issue 25/12, 2018, Page(s) 3329-3341.e5, ISSN 2211-1247
DOI: 10.1016/j.celrep.2018.11.083

Transcriptional control of macrophage polarisation in type 2 diabetes

Author(s): Karima Drareni, Jean-François Gautier, Nicolas Venteclef, Fawaz Alzaid
Published in: Seminars in Immunopathology, 2019, ISSN 1863-2297
DOI: 10.1007/s00281-019-00748-1

Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα

Author(s): Ning Liang, Anastasius Damdimopoulos, Saioa Goñi, Zhiqiang Huang, Lise-Lotte Vedin, Tomas Jakobsson, Marco Giudici, Osman Ahmed, Matteo Pedrelli, Serena Barilla, Fawaz Alzaid, Arturo Mendoza, Tarja Schröder, Raoul Kuiper, Paolo Parini, Anthony Hollenberg, Philippe Lefebvre, Sven Francque, Luc Van Gaal, Bart Staels, Nicolas Venteclef, Eckardt Treuter, Rongrong Fan
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-09524-z

Glucagon-like peptide 1 receptor agonists, diabetic retinopathy and angiogenesis: The AngioSafe type 2 diabetes study

Author(s): Bénédicte Gaborit, Jean-Baptiste Julla, Samaher Besbes, Matthieu Proust, Clara Vincentelli, Benjamin Alos, Patricia Ancel, Fawaz Alzaid, Rodrigue Garcia, Philippe Mailly, Florence Sabatier, Maud Righini, Pierre Gascon, Frédéric Matonti, Marie Houssays, Louisa Goumidi, Lucile Vignaud, Xavier Guillonneau, Ali Erginay, Bénédicte Dupas, Marie-Louise Jennifer, Marianne Autié, Tiphaine Vidal-Trec
Published in: The Journal of Clinical Endocrinology & Metabolism, 2019, ISSN 0021-972X
DOI: 10.1210/clinem/dgz069

Plasma Copeptin and Risk of Lower-Extremity Amputation in Type 1 and Type 2 Diabetes

Author(s): Louis Potier, Ronan Roussel, Michel Marre, Petter Bjornstad, David Z. Cherney, Ray El Boustany, Frédéric Fumeron, Nicolas Venteclef, Jean-François Gautier, Samy Hadjadj, Kamel Mohammedi, Gilberto Velho
Published in: Diabetes Care, Issue 42/12, 2019, Page(s) 2290-2297, ISSN 0149-5992
DOI: 10.2337/dc19-1062