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Cell-Based Models for Neurodegeneration Study and Use in Screening

Deliverables

CNS cell product and product information for single cell-type model

Produce Product Information Sheet describing 3D+ neural single-cell product.

CNS cell product and product information for dual cell-type model

Assemble and process-test dual-cell 3D+ production SOPs. Produce Product Information Sheet describing 3D+ neural dual-cell product

Documents defining technical performance and applications of 3D printed cell models

1. Standard Operating Procedures for 3D neurodegenerative therapeutic screening will be written. (M19) 2. Manufacturing protocols for 3D neural model(s) will be developed and ratified. (M21) 3. Materials and material supply arrangements will be consolidated (M21) 4. CNS cell product and product information for a single cell-type model will be produced. (M21) 5. CNS cell product and product information for a dual cell-type model will be produced. (M24) 6. The Deliverable outcome will be commercially-ready neurodegenerative screening services in 2D and 3D formats. (M24)

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