Objective In this project, the consortium will develop FAST-bact kits, a breakthrough test method to rapidly determine antibiotic drug susceptibility (AST), which will improve treatment of patients with serious bacterial infections. The current methodology in AST has a turnaround time of at least 24 hours, and up to 48 hours in case of blood cultures, whereas this novel flow cytometry-based test delivers results within 1-2 h. This will enable clinicians to start optimal antibiotic treatment as soon as possible, with a major impact on health and quality of life of patients and on health care costs.Resistance to antibiotic treatment leads to difficulties in the treatment of patients with bacterial infections. The FAST-bact project will have great impact on treatment of patients with (resistant) bacterial infections; a susceptibility report in useful time will reduce the use of broad spectrum or last line antibiotics. The FAST-bact tests will be marketed to clinical and microbiology diagnostic laboratories, in order to perform fast and accurate AST testing and optimize treatment for these patients. The tests will be marketed as a microplate-based kit, containing panels of antibiotics and compatible probes to determine the effect of the antibiotics, and including a software package for interpretation of results.The consortium will perform clinical validation of the tests against European and US standard methods. The previously designed decision support software, which allows fast and convenient result delivery, will be finalised and implemented. The technical file for regulatory proceedings will be drafted and large-scale production will be started. A commercialisation and dissemination plan will be drafted for market launch of the FAST-bact tests, first in Europe with expansion to other regions. In addition to these first products, opportunities will be explored to utilize the FAST-bact method for other tests, which will be included in the exploitation plan. Fields of science natural sciencescomputer and information sciencessoftwaremedical and health scienceshealth sciencespublic healthnatural sciencesbiological sciencesmicrobiologybacteriologymedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibioticsmedical and health sciencesbasic medicinepharmacology and pharmacydrug resistanceantibiotic resistance Programme(s) H2020-EC - Horizon 2020 Framework Programme Main Programme H2020-EU.3. - PRIORITY 'Societal challenges H2020-EU.2. - PRIORITY 'Industrial leadership' Topic(s) FTIPilot-01-2016 - Fast Track to Innovation Pilot Call for proposal H2020-FTIPilot-2016 See other projects for this call Sub call H2020-FTIPilot-2016-1 Funding Scheme IA - Innovation action Coordinator FASTINOV SA Net EU contribution € 1 319 062,50 Address Rua dr. francisco sa carneiro 312 loja c 4450-676 Matosinhos Portugal See on map Region Continente Norte Área Metropolitana do Porto Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 565 312,50 Participants (6) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UROBOPTICS - TECHNICAL CONSULTING & RESEARCH, LDA Portugal Net EU contribution € 267 890,00 Address Rua luis vaz de camoes edificio s jose 9c 3400 129 Oliveira do hospital See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Continente Centro (PT) Região de Coimbra Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 114 810,00 SERVICIO MADRILENO DE SALUD Spain Net EU contribution € 276 250,00 Address Plaza carlos trias bertran 7 28020 Madrid See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 EUROCLONE DIAGNOSTICA SRL Participation ended Italy Net EU contribution € 346 070,19 Address Via spezia 1 20142 Milano See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Nord-Ovest Lombardia Milano Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 148 315,80 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. EUROCLONE SPA Participation ended Italy Net EU contribution € 24 676,43 Address Via spezia 1 20142 Milano See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Nord-Ovest Lombardia Milano Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 10 575,61 PROFESS MEDICAL CONSULTANCY BV Netherlands Net EU contribution € 181 125,00 Address Paradijsvogel 31 1704 WP Heerhugowaard See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region West-Nederland Noord-Holland Alkmaar en omgeving Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 77 625,00 CLONIT SRL Italy Net EU contribution € 240 528,38 Address Via varese 20 20121 Milano See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Nord-Ovest Lombardia Milano Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 103 083,60
