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Paediatric Clinical Research Infrastructure Network

Objective

Children’s health is a major societal challenge for Europe and the world, requiring development of paediatric medicines and treatments strategies based on evidence derived from clinical trials demonstrating efficacy and safety in infants and children, rather than on uncritical extrapolation from adult data (over 50 % of the medicines used for children had not been tested in this specific age group).

Conducting clinical trials in children requires specific competences and infrastructure. ECRIN-ERIC (www.ecrin.org) is a generic infrastructure for multinational trial management, in any disease area. However it does not specifically address the paediatric needs in terms of trial management capacity. In its 2016 Roadmap, ESFRI suggested an upgrade of ECRIN to develop a common infrastructure for paediatric trial management through cooperation with the European Paediatric Clinical Trial Research Infrastructure (EPCTRI). The resulting PedCRIN project is also a unique opportunity to improve ECRIN business model and financial sustainability, attracting more industry-sponsored trials and more Member and Observer countries.

PedCRIN builds on five work packages : project coordination (WP1); establishment of a strategy and upgrade of the governance and business plan, through a Sustainability Board jointly involving the scientific partners and the government representatives (WP2); development of tools specific for paediatric and neonatal trials (WP3) (methodology, outcome measures, adverse event reporting, bio-sample management, ethical and regulatory database, monitoring, quality and certification); operational support provided as transnational access to a few pilot trials to test the updated organisation and tools (WP4); communication targeting user’s communities (including industry), policymakers, patient and parents’ empowerment (WP5). Two other ESFRI-landmarks, BBMRI-ERIC and EATRIS ERIC, will contribute to PedCRIN.

Call for proposal

H2020-INFRADEV-2016-1
See other projects for this call

Coordinator

ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK
Address
5 Rue Watt
75013 Paris
France
Activity type
Research Organisations
EU contribution
€ 1 530 125

Participants (15)

THE UNIVERSITY OF LIVERPOOL
United Kingdom
EU contribution
€ 325 875
Address
Brownlow Hill 765 Foundation Building
L69 7ZX Liverpool
Activity type
Higher or Secondary Education Establishments
CONSORZIO PER VALUTAZIONI BIOLOGICHE E FARMACOLOGICHE
Italy
EU contribution
€ 170 625
Address
Via Nicolo Putignani 178
70122 Bari
Activity type
Research Organisations
STICHTING RADBOUD UNIVERSITEIT

Participation ended

Netherlands
EU contribution
€ 155 625
Address
Houtlaan 4
6525 XZ Nijmegen
Activity type
Higher or Secondary Education Establishments
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 189 375
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ
Finland
EU contribution
€ 178 125
Address
Stenbackinkatu 9
00029 Helsinki
Activity type
Research Organisations
FUNDACIO PRIVADA PER A LA RECERCA I LA DOCENCIA SANT JOAN DE DEU
Spain
EU contribution
€ 196 875
Address
Calle Santa Rosa, 39-57
08950 Esplugues De Llobregat
Activity type
Research Organisations
SWISS CLINICAL TRIAL ORGANISATION
Switzerland
EU contribution
€ 48 750
Address
Effingerstrasse 35
3008 Bern
Activity type
Other
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 48 750
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
HELSE BERGEN HF*HAUKELAND UNIVERSITY HOSPITAL
Norway
EU contribution
€ 48 750
Address
Jonas Lies Vei 65
5021 Bergen
Activity type
Higher or Secondary Education Establishments
TARTU ULIKOOL
Estonia
EU contribution
€ 48 750
Address
Ulikooli 18
51005 Tartu
Activity type
Higher or Secondary Education Establishments
ARISTOTELIO PANEPISTIMIO THESSALONIKIS
Greece
EU contribution
€ 48 750
Address
Kedea Building, Tritis Septemvriou, Aristotle Univ Campus
54636 Thessaloniki
Activity type
Higher or Secondary Education Establishments
OKIDS GMBH
Austria
EU contribution
€ 48 750
Address
Zimmermannplatz 10
1090 Wien
Activity type
Other
THE NATIONAL CHILDREN'S RESEARCH CENTRE
Ireland
EU contribution
€ 48 750
Address
Our Lady's Children's Hospital Crumlin
DUBLIN 12 Dublin
Activity type
Other
VERENIGING SAMENWERKENDE OUDER- EN PATIENTENORGANISATIES
Netherlands
EU contribution
€ 185 625
Address
Vredehofstraat 31
3761HA Soest
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM
Netherlands
EU contribution
€ 22 500
Address
Geert Grooteplein 10 Zuid
6525 GA Nijmegen
Activity type
Higher or Secondary Education Establishments