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IN SITU IMAGING OF LIVING TISSUES WITH CELLULAR SPATIAL RESOLUTION

Objective

The main objective of HISTO-MRI project is to develop the technologies that will enable the non-invasive visualization of individual human cells in vivo and in real time, based on a radical new Magnetic Resonance Imaging concept: High Frequency Pulsed MRI. To accomplish this ambitious objective, several new challenging multidisciplinary technologies will have to be developed: 1) new method for the production of magnet coils, based on additive manufacturing technology, in order to stand very high currents at very high frequencies; 2) novel high frequency high voltage pulse power sources, based of semiconductor switches, to feed those magnet coils; and new pulse sequencing and computer algorithms to deal with and analyse the enormous amount of data. Therefore, this project has a foundational character, establishing the basis for a new field of research, pulsed MRI in the high frequency regime, which will radically advance MRI performance to micron resolution.
A Proof of Concept of the new technology will be accomplished through the visualization of a mouse brain at the neuron level. This new technology will enable transformative research in the fields of neurosciences, bioengineering, biophysics and experimental oncology

Call for proposal

H2020-FETOPEN-2016-2017

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Sub call

H2020-FETOPEN-1-2016-2017

Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Net EU contribution
€ 1 170 000,00
Address
Calle Serrano 117
28006 Madrid
Spain

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Research Organisations
Non-EU contribution
€ 0,00

Participants (4)

DANFYSIK AS
Denmark
Net EU contribution
€ 438 125,00
Address
Gregersensvej 8
2630 Taastrup

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
Net EU contribution
€ 250 000,00
Address
Albinusdreef 2
2333 ZA Leiden

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Region
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany
Net EU contribution
€ 708 125,00
Address
Hansastrasse 27c
80686 Munchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
Non-EU contribution
€ 0,00
TESORO IMAGING SL
Spain
Net EU contribution
€ 650 000,00
Address
Calle La Dorada 7-bungalow 28
03540 Alicante

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Este Comunitat Valenciana Alicante/Alacant
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00