Transcriptional control of plasma cell development and function

Project Information

PlasmaCellControl

Grant agreement ID: 740349

DOI

10.3030/740349

Project closed

EC signature date 28 June 2017

Start date 1 January 2018

End date 31 December 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 500 000,00

EU contribution

€ 2 500 000,00

Coordinated by

FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH
Austria

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response

Author(s): Vassilis Glaros; Vassilis Glaros; René Rauschmeier; Artem V. Artemov; Annika Reinhardt; Annika Reinhardt; Sebastian Ols; Sebastian Ols; Aikaterini Emmanouilidi; Charlotte Gustafsson; Yuanyuan You; Yuanyuan You; Claudio Mirabello; Åsa K. Björklund; Laurent Perez; Neil P. King; Robert Månsson; Robert Månsson; Davide Angeletti; Karin Loré; Karin Loré; Igor Adameyko; Igor Adameyko; Meinrad Buss
Published in: Immunity, Issue 14.09.2021, 2021, ISSN 1097-4180
Publisher: Cell Press
DOI: 10.1016/j.immuni.2021.08.017

Bhlhe40 function in activated B and TFH cells restrains the GC reaction and prevents lymphomagenesis

Author(s): René Rauschmeier; Annika Reinhardt; Charlotte Gustafsson; Vassilis Glaros; Artem V. Artemov; Josefine Dunst; Reshma Taneja; Igor Adameyko; Robert Månsson; Meinrad Busslinger; Taras Kreslavsky
Published in: Journal of Experimental Medicine, Issue 17.12.2021, 2021, ISSN 1540-9538
Publisher: Rockefeller University Press
DOI: 10.1084/jem.20211406

Igh and Igk loci use different folding principles for V gene recombination due to distinct chromosomal architectures of pro-B and pre-B cells

Author(s): Louisa Hill, Gordana Wutz, Markus Jaritz, Hiromi Tagoh, Lesly Calderón, Jan-Michael Peters, Anton Goloborodko, Meinrad Busslinger
Published in: Nature Communications, Issue 21.04.2023, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-37994-9

Comprehensive CRISPR-Cas9 screen identifies factors which are important for plasmablast development

Author(s): Theresa Pinter, Maria Fischer, Markus Schäfer, Michaela Fellner, Julian Jude, Johannes Zuber, Meinrad Busslinger, Miriam Wöhner
Published in: Frontiers in Immunology, Issue 15.09.2022, 2022, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2022.979606

Repression of the B cell identity factor Pax5 is not required for plasma cell development

Author(s): Grace J. Liu, Markus Jaritz, Miriam Wöhner, Benedikt Agerer, Andreas Bergthaler, Stephen G. Malin, Meinrad Busslinger
Published in: Journal of Experimental Medicine, Issue 217/11, 2020, ISSN 0022-1007
Publisher: Rockefeller University Press
DOI: 10.1084/jem.20200147

The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells

Author(s): Miriam Wöhner; Theresa Pinter; Peter Bönelt; Astrid Hagelkruys; Daniela Kostanova-Poliakova; Johannes Stadlmann; Stephen F. Konieczny; Maria Fischer; Markus Jaritz; Meinrad Busslinger
Published in: Frontiers in Immunology, Issue 21.12.2021, 2022, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2022.859598

Pax5 regulates B cell immunity by promoting PI3K signaling via PTEN down-regulation.

Author(s): Lesly Calderón; Karina Schindler; Stephen Malin; Stephen Malin; Alexandra Schebesta; Qiong Sun; Tanja A. Schwickert; Chiara Alberti; Maria Fischer; Markus Jaritz; Hiromi Tagoh; Anja Ebert; Martina Minnich; Adrian Liston; Luisa Cochella; Meinrad Busslinger
Published in: Science Immunology, Issue 27.07.2021, 2021, ISSN 2470-9468
Publisher: AAAS
DOI: 10.1126/sciimmunol.abg5003

Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion

Author(s): Louisa Hill, Anja Ebert, Markus Jaritz, Gordana Wutz, Kota Nagasaka, Hiromi Tagoh, Daniela Kostanova-Poliakova, Karina Schindler, Qiong Sun, Peter Bönelt, Maria Fischer, Jan-Michael Peters, Meinrad Busslinger
Published in: Nature, Issue 01.07.2020, 2020, ISSN 1476-4687
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-020-2454-y