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INTEGRATION AND PROPAGATION OF IMMUNOLOGICAL SIGNALS DURING CANCER AND INFECTION

Publications

Single-cell imaging of CAR T cell activity in vivo reveals extensive functional and anatomical heterogeneity

Author(s): Marine Cazaux, Capucine L. Grandjean, Fabrice Lemaître, Zacarias Garcia, Richard J. Beck, Idan Milo, Jérémy Postat, Joost B. Beltman, Eleanor J. Cheadle, Philippe Bousso
Published in: The Journal of Experimental Medicine, Issue 216/5, 2019, Page(s) 1038-1049, ISSN 0022-1007
DOI: 10.1084/jem.20182375

The immune system profoundly restricts intratumor genetic heterogeneity

Author(s): Idan Milo, Marie Bedora-Faure, Zacarias Garcia, Ronan Thibaut, Leïla Périé, Guy Shakhar, Ludovic Deriano, Philippe Bousso
Published in: Science Immunology, Issue 3/29, 2018, Page(s) eaat1435, ISSN 2470-9468
DOI: 10.1126/sciimmunol.aat1435

A Metabolism-Based Quorum Sensing Mechanism Contributes to Termination of Inflammatory Responses

Author(s): Jérémy Postat, Romain Olekhnovitch, Fabrice Lemaître, Philippe Bousso
Published in: Immunity, Issue 49/4, 2018, Page(s) 654-665.e5, ISSN 1074-7613
DOI: 10.1016/j.immuni.2018.07.014

Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division

Author(s): Armelle Bohineust, Zacarias Garcia, Hélène Beuneu, Fabrice Lemaître, Philippe Bousso
Published in: The Journal of Experimental Medicine, Issue 215/5, 2018, Page(s) 1481-1492, ISSN 0022-1007
DOI: 10.1084/jem.20171708

Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment

Author(s): Ronan Thibaut, Pierre Bost, Idan Milo, Marine Cazaux, Fabrice Lemaître, Zacarias Garcia, Ido Amit, Béatrice Breart, Clémence Cornuot, Benno Schwikowski, Philippe Bousso
Published in: Nature Cancer, Issue 1/3, 2020, Page(s) 302-314, ISSN 2662-1347
DOI: 10.1038/s43018-020-0038-2

Tumor Immunosurveillance and Immunotherapies: A Fresh Look from Intravital Imaging

Author(s): Morgane Boulch, Capucine L. Grandjean, Marine Cazaux, Philippe Bousso
Published in: Trends in Immunology, Issue 40/11, 2019, Page(s) 1022-1034, ISSN 1471-4906
DOI: 10.1016/j.it.2019.09.002

Optogenetic manipulation of calcium signals in single T cells in vivo

Author(s): Armelle Bohineust, Zacarias Garcia, Béatrice Corre, Fabrice Lemaître, Philippe Bousso
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-14810-2

Quorum Sensing by Monocyte-Derived Populations

Author(s): Jérémy Postat, Philippe Bousso
Published in: Frontiers in Immunology, Issue 10, 2019, ISSN 1664-3224
DOI: 10.3389/fimmu.2019.02140