Encapsulated eukaryotic ribosome assembly

Project Information

Glowsome

Grant agreement ID: 741781

DOI

10.3030/741781

Project closed

EC signature date 30 June 2017

Start date 1 September 2017

End date 31 August 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Non-peer reviewed articles (5)

A Homologous Recombination System to Generate Epitope-Tagged Target Genes in Chaetomium thermophilum: A Genetic Approach to Investigate Native Thermostable Proteins

Author(s): Nikola Kellner, Sabine Griesel, Ed Hurt
Published in: International Journal of Molecular Sciences, Issue 23 (6), 2022, Page(s) 3198, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23063198

Global Transcriptome Characterization and Assembly of the Thermophilic Ascomycete Chaetomium thermophilum

Author(s): Amit Singh, Géza Schermann, Sven Reislöhner, Nikola Kellner, Ed Hurt, Michael Brunner
Published in: Genes, Issue 12, 2021, Page(s) 1549, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes12101549

Eukaryotic Ribosome Assembly

Author(s): Jochen Baßler, Ed Hurt
Published in: Annual Review of Biochemistry, Issue 88/1, 2019, Page(s) 281-306, ISSN 0066-4154
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-biochem-013118-110817

Emergence of the primordial pre-60S from the 90S pre-ribosome

Author(s): Sherif Ismail, Dirk Flemming, Matthias Thoms, Jose Vincente Gomes-Filho, Lennart Randau, Roland Beckmann, Ed Hurt
Published in: Cell Reports, Issue 39(1), 2022, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2022.110640

Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome

Author(s): Benjamin Lau, Jingdong Cheng, Dirk Flemming, Giuseppe La Venuta, Otto Berninghausen, Roland Beckmann, Ed Hurt
Published in: Mol Cell, Issue 81(2), 2021, Page(s) 293-303.e4., ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2020.11.009

Peer reviewed articles (10)

In vitro structural maturation of an early stage pre-40S particle coupled with U3 snoRNA release and central pseudoknot formation

Author(s): Jingdong Cheng, Giuseppe La Venuta, Benjamin Lau, Otto Berninghausen, Roland Beckmann, Ed Hurt
Published in: Nucleic Acids Research, Issue Vol. 50, No. 20, 2022, Page(s) 11916-11923, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkac910

Cms1 coordinates stepwise local 90S pre-ribosome assembly with timely snR83 release

Author(s): Benjamin Lau, Olga Beine-Golovchuk, Markus Kornprobst, Jingdong Cheng, Dieter Kressler, Beáta Jády, Tamás Kiss, Roland Beckmann, Ed Hurt
Published in: Cell Reports, Issue 2022 Nov 22;41(8):111684, 2022, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2022.111684

90S pre-ribosome transformation into the primordial 40S subunit

Author(s): Jingdong Cheng , Benjamin Lau, Giuseppe La Venuta, M. Ameismeier, Otto Berninghausen, Ed Hurt, Roland Beckmann
Published in: Science, Issue 00368075, 2020, Page(s) 1470-1476, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abb4119

Mpp10 represents a platform for the interaction of multiple factors within the 90S pre-ribosome

Author(s): Bebiana Sá-Moura, Markus Kornprobst, Satyavati Kharde, Yasar Luqman Ahmed, Gunter Stier, Ruth Kunze, Irmgard Sinning, Ed Hurt
Published in: PLOS ONE, Issue 12/8, 2017, Page(s) e0183272, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0183272

3.2-Å-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage

Author(s): Jingdong Cheng, Nikola Kellner, Otto Berninghausen, Ed Hurt, Roland Beckmann
Published in: Nature Structural & Molecular Biology, Issue 24/11, 2017, Page(s) 954-964, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/nsmb.3476

Interdependent action of KH domain proteins Krr1 and Dim2 drive the 40S platform assembly

Author(s): Miriam Sturm, Jingdong Cheng, Jochen Baßler, Roland Beckmann, Ed Hurt
Published in: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-017-02199-4

Eukaryotic ribosome assembly, transport and quality control

Author(s): Cohue Peña, Ed Hurt, Vikram Govind Panse
Published in: Nature Structural & Molecular Biology, Issue 24/9, 2017, Page(s) 689-699, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/nsmb.3454

Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration

Author(s): Jingdong Cheng, Jochen Baßler, Paulina Fischer, Benjamin Lau, Nikola Kellner, Ruth Kunze, Sabine Griesel, Martina Kallas, Otto Berninghausen, Daniela Strauss, Roland Beckmann, Ed Hurt
Published in: Molecular Cell, Issue 75/6, 2019, Page(s) 1256-1269.e7, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.06.032

A Puzzle of Life: Crafting Ribosomal Subunits

Author(s): Dieter Kressler, Ed Hurt, Jochen Baßler
Published in: Trends in Biochemical Sciences, Issue 42/8, 2017, Page(s) 640-654, ISSN 0968-0004
Publisher: Elsevier BV
DOI: 10.1016/j.tibs.2017.05.005

The nucleoplasmic phase of pre-40S formation prior to nuclear export

Author(s): Jingdong Chen, Benjamin Lau, Matthias Thoms, Michael Ameismeier, Otto Berninghausen, Ed Hurt, Roland Beckmann
Published in: Nucleic Acids Research, Issue Vol. 50, No. 20, 2022, Page(s) 11924–11937, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkac961

Book chapters (1)

Transformation of Chaetomium thermophilum and affinity-purification of Native tTermostable Protein Complexes

Author(s): Nikola Kellner, Ed Hurt
Published in: Methods in Molecular Biology, Issue 2502, 2022, Page(s) 35-50, ISBN 978-1-0716-2337-4
Publisher: Springer Nature
DOI: 10.1007/978-1-0716-2337-4_2