Clonal Deletion versus Clonal Diversion: Footprints of Self-Tolerance in the T Cell Repertoire

Project Information

TOLERANCE FOOTPRINT

Grant agreement ID: 742290

DOI

10.3030/742290

Project closed

EC signature date 5 July 2017

Start date 1 October 2017

End date 30 September 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 414 500,00

EU contribution

€ 2 414 500,00

Coordinated by

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany

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Publications

Peer reviewed articles (2)

Central CD4+ T cell tolerance: deletion versus regulatory T cell differentiation

Author(s): Ludger Klein, Ellen A. Robey, Chyi-Song Hsieh
Published in: Nature Reviews Immunology, Issue 19/1, 2019, Page(s) 7-18, ISSN 1474-1733
Publisher: Nature Publishing Group
DOI: 10.1038/s41577-018-0083-6

Inventories of naive and tolerant mouse CD4 T cell repertoires reveal a hierarchy of deleted and diverted T cell receptors

Author(s): Tobias Hassler, Emanuel Urmann, Sebastian Teschner, Christine Federle, Thamotharampillai Dileepan, Kilian Schober, Marc K. Jenkins, Dirk H. Busch, Maria Hinterberger, Ludger Klein
Published in: Proceedings of the National Academy of Sciences, Issue 116/37, 2019, Page(s) 18537-18543, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1907615116