The protocol-defined field activities have now been completed. They field study examinations were started in March 2018 in five study centres in Finland (cities of Turku, Tampere, Helsinki, Kuopio and Oulu), and ended in February 2020. In total, 7,345 individuals participated in the study: G1 N=2,128 (66.2% participation rate); G0 N=2,460 (62.8%), and G2 N=2,757 (48.6%). In total, 1,378 sperm samples have been collected for RNA sequencing across three generations of males aged 18 and over. We are presently processing the data and performing laboratory analyses of the collected samples.