Commercialization of high-value chemical production in moss

Project Information

TYCHOBIO

Grant agreement ID: 745412

DOI

10.3030/745412

Project closed

EC signature date 1 December 2016

Start date 1 March 2017

End date 31 August 2017

Funded under

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology

Total cost

€ 71 429,00

EU contribution

€ 50 000,00

Coordinated by

TYCHOBIO IVS
Denmark

Periodic Reporting for period 1 - TYCHOBIO (Commercialization of high-value chemical production in moss)

Reporting period: 2017-03-01 to 2017-08-31

Summary of the context and overall objectives of the project

The current world population of 7.2bn people is projected by the UN to rise to 9.6bn in 2050. This growth will create enormous pressure on world food production. An increased focus on specific ingredients properties will play a crucial role in this context. Many ingredients originate from specialty plant chemicals, but these are often present in low quantities in the native plant constituting less than 1% of total mass. TychoBio provides a platform for green and sustainable production of plant specialty chemicals used in the personal care, food, pharmaceutical and animal feed industry. The development of our platform enables us to quickly deliver specific products to our customers through a B2B strategy. TychoBio is exploring the use of the moss Physcomitrella patens that only requires light, water and a minimum supply of nutrients to produce high-value ingredients while simultaneously removing CO2 from the atmosphere. The moss has the ability to be engineered to produce a large range of industrial relevant specialized plant chemicals.

Work performed from the beginning of the project to the end of the period covered by the report and main results achieved so far

Throughout this SME Phase I project we have explored three different work packages: WP1: Investigation of the patentability of our platform
WP2: Upscaling in a relevant environment
WP3: Feasibility report
We have generated a comprehensive feasibility study of our business concept.
A professional freedom-to-operate analysis was conducted during the project, which stated that we have freedom-to-operate when developing new genetic tools to optimize moss for the production of specialty plant chemicals. We plan to submit a patent application covering the production of an antioxidant in our moss platform late 2017.
We investigated several upscaling methods, including Wave plastic bags, tubular photobioreactors and simple glass bioreactors for in-house use. We showed that moss grows very fast in our bioreactor and we expect to be able to reduce the growth-rate in future tests. In the business plan we have identified our target market, made a customer profiling, a business model and initiated customer contact which resulted in positive feedback and proof that our platform has industrial interest.

Progress beyond the state of the art and expected potential impact (including the socio-economic impact and the wider societal implications of the project so far)

The evaluation of the feasibility of our business concept has led to several positive outcomes and prospects. We thus conclude that TychoBio have the potential to become a significant player within the synthetic biology sector in Europe by producing plant specialty chemicals for the food, animal feed, cosmetic and pharmaceutical industry.

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