Objective
Cyanobacteria are versatile photosynthetic organisms that have attracted interest as a sustainable biotechnological host chassis. The toolkit for these organisms is growing fast, however, limitations such as low productivities are still a major drawback for this emerging technology. Cynthetica will address the issue of recombinant product yields and develop two separate tools that can be universally applied for product synthesis in cyanobacteria.
WP1 incorporates the development of an ‘anchor tool’ to increase stability and the interaction of membrane-bound recombinant enzymes, such as cytochrome P450s, in cyanobacterial thylakoid membranes via membrane anchor engineering. This will lead to improved metabolic fluxes through the pathway and, thus, higher product yields. In WP2 a ‘capsule tool’ will be developed. Cyanobacterial strains with proteinaceous shells, so-called microcompartments, will be generated to encapsulate biosynthetic pathways for improved product yields. In WP3 the Cynthetica tools will be tested at scale for their applicability in an industrial setting during a secondment with the partner organisation AGROT.
The intersectoral knowledge transfer between UCPH, AGROT and the fellow will allow for timely progression of the project, delivering cutting edge science and allowing the fellow to grow not only her scientific skill set but also reach maturity as an academic researcher. Thanks to the state-of-the art equipment and expertise available at UCPH and AGROT the project will have most favourable conditions to be a success. The Horizon 2020 framework highlights the need to develop a sustainable biotechnology sector in Europe. Cynthetica will position itself at the forefront of this emerging field by delivering innovative synthetic biology tools for establishing cyanobacteria as a powerful photosynthetic production platform.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences synthetic biology
- engineering and technology environmental engineering energy and fuels
- natural sciences earth and related environmental sciences atmospheric sciences climatology climatic changes
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
See all projects funded under this programme -
H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1165 Kobenhavn
Denmark
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.