An Integrated Computational and Experimental Approach to Rapid Synthesis of Highly Selective Dual-Targeted HDAC/CK2, MMP2/CK2 Inhibitors

Project Information

DUALITY

Grant agreement ID: 746225

DOI

10.3030/746225

Project terminated on 31 January 2020

EC signature date 21 March 2017

Start date 10 April 2018

End date 9 April 2020

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 170 121,60

EU contribution

€ 170 121,60

Coordinated by

FUNDACION UNIVERSITARIA SAN PABLO-CEU
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (3)

Molecular Imaging Probes Based on Matrix Metalloproteinase Inhibitors (MMPIs)

Author(s): Rangasamy, Geronimo, Ortín, Coderch, Zapico, Ramos, de Pascual-Teresa
Published in: Molecules, Issue 24/16, 2019, Page(s) 2982, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24162982

New Dual CK2/HDAC1 Inhibitors with Nanomolar Inhibitory Activity against Both Enzymes

Author(s): Loganathan Rangasamy, Irene Ortín, José María Zapico, Claire Coderch, Ana Ramos, Beatriz de Pascual-Teresa
Published in: ACS Medicinal Chemistry Letters, 2020, ISSN 1948-5875
Publisher: American Chemical Society
DOI: 10.1021/acsmedchemlett.9b00561

Design and Synthesis of Water-Soluble and Potent MMP-13 Inhibitors with Activity in Human Osteosarcoma Cells

Author(s): Jose Maria Zapico, Lourdes Acosta, Miryam Pastor, Loganathan Rangasamy, Laura Marquez-Cantudo, Claire Coderch, Irene Ortin, Maria Nicolau-Sanus, Leonor Puchades-Carrasco, Antonio Pineda-Lucena, Alejandro Majali-Martinez, Pilar Ramos, Beatriz de Pascual-Teresa, Ana Ramos
Published in: International Journal of Molecular Sciences, Issue 22/18, 2021, Page(s) 9976, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22189976