An Integrated Computational and Experimental Approach to Rapid Synthesis of Highly Selective Dual-Targeted HDAC/CK2, MMP2/CK2 Inhibitors

Publications

Peer reviewed articles (3)

Molecular Imaging Probes Based on Matrix Metalloproteinase Inhibitors (MMPIs)

Author(s): Rangasamy, Geronimo, Ortín, Coderch, Zapico, Ramos, de Pascual-Teresa
Published in: Molecules, 24/16, 2019, Page(s) 2982, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24162982

New Dual CK2/HDAC1 Inhibitors with Nanomolar Inhibitory Activity against Both Enzymes

Author(s): Loganathan Rangasamy, Irene Ortín, José María Zapico, Claire Coderch, Ana Ramos, Beatriz de Pascual-Teresa
Published in: ACS Medicinal Chemistry Letters, 2020, ISSN 1948-5875
Publisher: American Chemical Society
DOI: 10.1021/acsmedchemlett.9b00561

Design and Synthesis of Water-Soluble and Potent MMP-13 Inhibitors with Activity in Human Osteosarcoma Cells

Author(s): Jose Maria Zapico, Lourdes Acosta, Miryam Pastor, Loganathan Rangasamy, Laura Marquez-Cantudo, Claire Coderch, Irene Ortin, Maria Nicolau-Sanus, Leonor Puchades-Carrasco, Antonio Pineda-Lucena, Alejandro Majali-Martinez, Pilar Ramos, Beatriz de Pascual-Teresa, Ana Ramos
Published in: International Journal of Molecular Sciences, 22/18, 2021, Page(s) 9976, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22189976