Objective
The methyl erythritol phosphate (MEP) pathway in the chloroplast synthesizes isoprenoids (a class of hydrocarbons) by almost exclusively utilising carbon and energy supplied by photosynthesis in plant leaves. Volatile isoprenoids (antioxidant hydrocarbons), isoprenoid-type cytokinins (plant ‘youth’ hormone), carotenoids (photoprotective pigments), and abscisic acid (plant ‘stress’ hormone) are some of the active isoprenoid end-products of the MEP pathway that play a role in leaf senescence. We aim to quantify and model age-specific relationships between photosynthesis and MEP pathway during natural and abiotic-stress induced leaf senescence in three different plant systems: wheat (a crop), poplar (a plantation tree) and Arabidopsis (the model species for genomics). By combining leaf age-specific chloroplast energy balance estimation through photosynthesis modelling, quantification of carbon demands of isoprenoid biosynthesis using stable isotope tracing and advanced real-time analytical techniques, monitoring plastome and chloroplast integrity, and whole-epigenome sequencing, LEAF-OF-LIFE will (i) develop a versatile quantitative method for predicting leaf senescence trajectories based on the relationship between photosynthesis and isoprenoid biosynthesis during senescence and (ii) identify novel gene cascades involved in epigenomic regulation of the MEP pathway during natural and abiotic stress-induced leaf senescence. A thorough understanding of leaf age-specific changes in energy and carbon demands of isoprenoid biosynthesis will provide a strong mechanistic basis to phenology models of autumn senescence in deciduous trees. Discovery of novel gene regulatory cascades involved in age-specific changes in isoprenoid biosynthesis will be spearheading new research intended to target MEP pathway so as to alter leaf life span (delay stress-induced leaf senescence) in major global crops and plantations.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences chemical sciences organic chemistry volatile organic compounds
- natural sciences chemical sciences organic chemistry hydrocarbons
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
- natural sciences biological sciences botany
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
00185 Roma
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.