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Role of a novel proteasome-associated DUB – A boon for therapeutics

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Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations

Author(s): Zhanyu Ding, Cong Xu, Indrajit Sahu, Yifan Wang, Zhenglin Fu, Min Huang, Catherine C.L. Wong, Michael H. Glickman, Yao Cong
Published in: Molecular Cell, 2019, ISSN 1097-2765
DOI: 10.1016/j.molcel.2019.01.018

Signature activities of 20S proteasome include degradation of the ubiquitin-tag with the protein under hypoxia

Author(s): Indrajit Sahu, Sachitanand M Mali, Prasad Sulkshane, Andrey Rozenberg, Cong Xu, Roni Morag, Manisha Priyadarsini Sahoo, Sumeet K Singh, Zhanyu Ding, Yifan Wang, Sharleen Day, Yao Cong, Oded Kleifeld, Ashraf Brik, Michael H Glickman
Published in: BioRxIV, 2019
DOI: 10.1101/2019.12.20.883942