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A Low-cost disposAble eleCTrochemical biOsensor for Point Of Care (POC) hypolactasia diagnostic testing

Objective

LACTOPOC is a multidisciplinary research and training programme targeted to provide Dr. Macia-Gonzalez, an expert in electrochemical analytical platforms design, with new entrepreneurial and scientific skills on translation of innovative biosensor technology into Point of Care (POC) diagnostic devices.
LACTOPOC main scientific goal is to develop a low-cost and highly reproducible biosensor manufacturing platform technology for POC hypolactasia diagnostic testing. The project is based on the combination of two-well established analytical tools, i.e. paper-based microfluidics and electrochemistry, together with mass-manufacturing technologies for innovative design such wax and screen printing.
Hypolactasia is related to low levels or reduced activity of intestinal lactase, the enzyme responsible for the hydrolysis of lactose during its digestion. Undigested lactose after intake of dairy products is then accumulated in the intestine causing flatulence, abdominal pain and diarrhea in the individuals suffering from this malfunction. Despite it affects over half of the world population, its diagnosis remains challenging because associated symptoms are not specific and available methods for its diagnosis are unspecific and rely on trained staff and complex equipment.
LACTOPOC will bring forward the technology developed by OSASEN for determination of D-xylose in urine and venous blood samples based on an electrochemical biosensor lab-prototype into a robust POC device with high sensitivity and reproducibility. The device will be able to detect and quantify accurately minimum D-Xylose concentration levels in a simple drop of human capillary blood sample. This novel POC biosensor device will assist LacTEST®, a non-invasive diagnostic test based on the synthetic analog gaxilose recently developed by VenterPharma, to become the first promising POC diagnostic testing for hypolactasia available in the market, leveraging their impact on patients and health care providers.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

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Funding Scheme

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MSCA-IF-EF-SE - Society and Enterprise panel

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Call for proposal

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(opens in new window) H2020-MSCA-IF-2016

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Coordinator

BIOLAN HEALTH SL
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 158 121,60
Address
C/ LAIDA BIDEA EDIFICIO 409 DEL COMPLEJO PARQUE TECNOLOGICO DE BIZKAIA
48170 ZAMUDIO
Spain

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Noreste País Vasco Bizkaia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 158 121,60
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