"More than 60% of the worldwide population live on or near a coastline. These areas, at the interface between land and sea, are of considerable socio-cultural and economic importance (e.g. for tourism). They also host extraordinary biodiversity that supports many significant services to humankind such as maintenance of fisheries, water purification or carbon sequestration. However, human activities have deleterious effects the world’s coastal environments and their biodiversity. Among the main stressors are water pollution, urban development and habitat degradation, introduction of alien species, climate changes and their associated effects (e.g. water temperature increase, ocean acidification, sea-level rise). Yet, although these pressures often act simultaneously, their cumulative impacts on coastal biodiversity are poorly understood, mainly for two reasons. First, traditional approaches for monitoring coastal biodiversity present multiple constraints that limit observations to a small number of taxa, and restrain the extent of studies. Second, studies often focus on the impact of a single stressor and ignore interacting effects between stressors. Therefore, to efficiently improve the health of coastal environments, we need more integrative approaches to improve the monitoring of coastal biodiversity, and to disentangle the effects of the different stressors on biodiversity. To reach this goal, and thus support adapted management strategies, the TEAM-Coast project aims at developing a new generation of tools, based on molecular approaches named ‘environmental DNA’ (i.e. the study of genetic material retrieved in environmental samples such as water and sediments). These environmental DNA-based methods for monitoring biodiversity (also called ""eDNA biomonitoring"") seek to identify species living in a given area from DNA they release in the environment. These approaches have proved to be powerful tools for obtaining comprehensive and standardised biodiversity datasets in a relatively rapid and cost-efficient way. The TEAM-Coast project pursues thus three main objectives. The first one aims at developing protocols for the large-scale implementation of eDNA biomonitoring in costal environments. The second one aims at precisely describing the diversity and distribution of species assemblages, including species of ecological and economical interest, and at the same time identifying each of the main anthropogenic pressures, in order to finally assess the responses of communities to each of these pressures acting jointly. Ultimately, this project aims at developing ecological risk assessment models, based on environmental DNA data, and test management scenarios for striking the balance between human activities and the ecological integrity of coastal environments."