Objective
The perception of complex visual scenes requires active processing by the brain. The visual cortex is hierarchically organized in several areas which are linked by connections projecting from lower to higher areas (feedforward) and connections projecting from higher to lower areas (feedback). More complicated processing occurs in higher areas such as V4, where neurons encode which side of a border belongs to a figure. Feedback connections are large in number but their function is poorly understood. An important role for feedback has been proposed in probabilistic inference, whereby cortical areas “infer” the reality in the external world based on the sensory information they receive from lower areas, combined with prior hypotheses projected down from higher areas.
In this project we propose a causal study of the role of feedback connections from area V4 to lower areas in the inference of figure location. We will record neural activity simultaneously in V4 and V1, and V4 and V2, using microelectrodes in the awake rhesus macaque, during the presentation of figures on a background, while we reversible activate or suppress a well-defined patch in V4 using an opsin. By training the animal to perform a figure detection task we can link the perturbation of neural activity to perception.
The beneficiary is the Netherlands Institute for Neuroscience, where the researcher will be advised by Prof. Pieter Roelfsema, an internationally recognized expert in visual neuroscience with experience with neurophysiology, behavioral studies and computational neuroscience. There will be an outgoing phase of two years, during which the researcher will perform animal experiments in the laboratory of Prof. John Reynolds in the Salk Institute for Biological Studies, who has extensive experience with optogenetics and viral targeting.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- social sciences psychology behavioural psychology
- natural sciences biological sciences neurobiology computational neuroscience
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1011 JV AMSTERDAM
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.