Objective Human fluid intelligence is characterized by a structured sequence of cognition, resulting in efficient application of rules to novel problems. In the brain, metabolic neuroimaging and lesion studies have linked fluid intelligence to a specific frontoparietal network, here called the multiple-demand (MD) network, comprising regions of lateral frontal, insular, dorsomedial frontal and parietal cortex. But how do MD functions determine fluid intelligence across stages of cognition? My extensive expertise in electroencephalography (EEG) source analyses and neural pattern classification techniques will allow me to assess time-resolved neural representations of novel rules in MD and perceptual cortex as a function of fluid intelligence, as well as the causal impact of MD cortex on earliest stages of perceptual encoding. Higher- and lower-intelligent subjects’ electrophysiological (EEG) and behavioural measures of novel rule implementation will be systematically analysed. Non-invasive neural stimulation (transcranial magnetic stimulation (TMS)) will be used in combination with EEG to draw causal conclusions on the specific role of MD and perceptual cortices in human fluid intelligence. My novel analysis approach may provide a new account on fluid intelligence: one aspect of low fluid intelligence may be the dysfunctional early filtering of task-relevant information in perceptual cortex, due to lack of top-down control from MD cortices, leading to sensory overload on later processing stages. The proposal’s outcomes will be both of high academic and commercial interest. Understanding the brain signatures underlying fluid intelligence is essential for more specific and cost-effective medical interventions. For example, decline of fluid intelligence due to healthy ageing is strongly correlated with high-cost medical conditions such as depression, which affect an increasing number of people in the ageing European population. Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2016 - Individual Fellowships Call for proposal H2020-MSCA-IF-2016 See other projects for this call Funding Scheme MSCA-IF-EF-ST - Standard EF Coordinator LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN Net EU contribution € 159 460,80 Address Geschwister scholl platz 1 80539 Muenchen Germany See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
