Objective
SeCtOR ENABleRs aims to develop a convenient kit for the production of partially customizable organs-on-chip. The main motivations that lead us to get involved in this effort are to provide the scientific community of an easy-to-use, economically convenient and standardized microfluidic platform. This is expected to facilitate and promote the diffusion of advanced 3D cell culture systems in routine analyses and make results obtained from different experiences/laboratories more comparable. In this view we envisage possible applications in the field of stem cell biology, personalized medicine, toxicology as well as advanced pre-clinical trials. The kit main components are an ad hoc designed thermoplastic chip and a set of collagenous formulations. The chip design will allow the integration of a thermo-controller device compatible with live cell imaging techniques. A biomimetic approach and a cell-friendly crosslinking strategy will allow to control the composition and the mechanical properties of the collagenous formulations, thus approaching the complexity of natural cell environment. The flexibility of the kit will be demonstrated by obtaining vascularized neuronal and bone models using commercially available cells. Although some risky steps areforeseeable, the innovation in this project is more represented by the concept of organs on chip platform standardization than in significant disruptive breakthroughs. We are convinced that the accessibility to a convenient, standardized and flexible platform is the key to exploit the huge potentialities demonstrated by microfluidics organs on chip. The implementation of the proposed multidisciplinary work plan in an industrial environment will contribute to obtain unconventional complementary skills; understanding of the industrial perspective and needs and will finally guarantee the full exploitation of the project outcomes by establishing future SME/academics collaboration projects.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy drug discovery
- medical and health sciences medical biotechnology cells technologies stem cells
- medical and health sciences health sciences personalized medicine
- medical and health sciences basic medicine immunology immunotherapy
- engineering and technology other engineering and technologies microtechnology organ on a chip
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-SE - Society and Enterprise panel
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
93100 Montreuil
France
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.