Objective
Ongoing search for renewable energy technologies is essential in Europe to tackle the continuous increase in demand and the environmental and ethical concerns. Hydrogen is a promising renewable fuel, but so far its production is not clean as the conventional industrial techniques start from fossil fuels. Production of H2 by biological, biotechnological or bioinspired methods would solve this problem and the study of FeFe-hydrogenases is a key step in this process. For this reason, the proposal is well aligned with the EU Societal Challenges in “Secure, clean and efficient energy”. FeFe-hydrogenases are efficient metalloenzymes that catalyse H2 production from water at high turnover rates, using Fe, rather than Pt active sites. Building on my previous experience with these enzymes, in this project I will apply a highly innovative approach to investigate how nature uses cheap iron to catalyse H2 production. Protein film infrared (IR) electrochemistry was recently developed by Prof Vincent at the University of Oxford, allowing electrochemical triggering of enzyme catalysis with simultaneous IR spectroscopic study of how the enzyme works. This will provide a deep understanding of enzyme structure/function relationships, from coordinated electron and proton transfer to structural rearrangements at the Fe site. Due to my prior expertise in FeFe hydrogenases which are not studied in the host group, and Oxford’s excellence in bio-spectroscopy, the Fellowship will promote exceptional bidirectional knowledge transfer. Dissemination of research through Oxford’s outreach programs will increase the impact of the project to varied audiences. Access to the well-established training and career development activities in Oxford, and the world-class programs of visiting speakers, will advance my career as I gain new knowledge and skills, enhance my scientific profile by acquiring international experience, expand my scientific horizon, strengthen my skills, and build new networks.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences chemical sciences electrochemistry
- natural sciences chemical sciences catalysis
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
- natural sciences biological sciences molecular biology structural biology
- natural sciences physical sciences optics spectroscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
OX1 2JD Oxford
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.