Objective
Head direction (HD) cells provide directional information during spatial navigation and thus act as an
internal compass. The goal of this study is to understand how the HD circuit creates a lasting neural trace of
transient directional changes. Cells selective for HD have been identified in several brain regions, including
the retrosplenial cortex (RSC), and display persistent activity in response to transient vestibular turning
cues. Although a well-established theoretical framework proposes an elegant circuitry for achieving this
self-sustaining activity, biological evidence for such a circuit is lacking. Studies of HD circuitry have faced
significant challenges due to the necessity of functional monitoring at large and small scales in vivo, and
precise stimulus control. This study will take advantage of recent advances allowing the targeting of specific
cells and their inputs for chronic two-photon imaging in the awake, head-fixed, and passively rotated mouse.
Experiments will aim to (1) determine the spatial and temporal organization of HD-tuned responses in RSC,
and (2) functionally characterize the presynaptic inputs of HD cells. This information will validate or reject
a prominent theory of neural network organization, and provide unprecedented insight into a poorly
understood but critical brain function.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences zoology mammalogy primatology
- natural sciences biological sciences neurobiology cognitive neuroscience
- natural sciences chemical sciences inorganic chemistry alkaline earth metals
- social sciences social geography transport navigation systems
- natural sciences computer and information sciences artificial intelligence computational intelligence
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
0313 Oslo
Norway
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.