Novel Antimicrobial Graphene Oxide-Lanthanide- Hydroxyapatite Composites as Therapeutic Materials in Bone Infection and Repair

Project Information

NOVA

Grant agreement ID: 753636

DOI 10.3030/753636

Closed project

EC signature date 24 February 2017

Start date 1 March 2017

End date 28 February 2019

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 195 454,80

EU contribution € 195 454,80

Coordinated by

THE UNIVERSITY OF BIRMINGHAM
United Kingdom

Objective

NOVA is an innovative multi- and inter-disciplinary Fellowship hosted by the University of Birmingham in the UK with the main aim to develop antimicrobial graphene oxide (GO)-lanthanide glasses (Ln)-hydroxyapatite (HA) composites for bone repair. Large bone defects and infections represent a major challenge for orthopaedic surgeons. Infections may be life-threatening or, commonly, associated with long-term disability and pose a serious and increasing threat to public health, especially when antimicrobial resistance is becoming a serious problem. It is therefore highly desirable to develop novel multi-functional systems that can exhibit antimicrobial properties for bone repair. Lanthanide glasses (Ln) and Graphene Oxide (GO) have shown very interesting properties, the first being used in sensing and imaging as well as enabling cell attachment and isomorphic replacements for calcium, the second being an antimicrobial. NOVA will develop a multifunctional composite system combining the useful properties of a lanthanide host glass with the antimicrobial activity of Graphene Oxide and the bioactivity of Hydroxyapatite (HA). The proposed research is a novel research direction, and there is no previously published research on what is proposed to be a new class of multi-functional composites.

Fields of science

• engineering and technology › materials engineering › colors
• engineering and technology › nanotechnology › nano-materials › two-dimensional nanostructures › graphene
• engineering and technology › materials engineering › composites
• engineering and technology › mechanical engineering › manufacturing engineering › additive manufacturing
• engineering and technology › materials engineering › ceramics

Programme(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2016 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2016

Funding Scheme

MSCA-IF-EF-ST - Standard EF

Coordinator

THE UNIVERSITY OF BIRMINGHAM

• Net EU contribution: € 195 454,80
• Address: Edgbaston ; B15 2TT Birmingham ; United Kingdom
• Region: West Midlands (England) › West Midlands › Birmingham
• Activity type: Higher or Secondary Education Establishments
• Total cost: € 195 454,80