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Novel Antimicrobial Graphene Oxide-Lanthanide- Hydroxyapatite Composites as Therapeutic Materials in Bone Infection and Repair

Objective

NOVA is an innovative multi- and inter-disciplinary Fellowship hosted by the University of Birmingham in the UK with the main aim to develop antimicrobial graphene oxide (GO)-lanthanide glasses (Ln)-hydroxyapatite (HA) composites for bone repair. Large bone defects and infections represent a major challenge for orthopaedic surgeons. Infections may be life-threatening or, commonly, associated with long-term disability and pose a serious and increasing threat to public health, especially when antimicrobial resistance is becoming a serious problem. It is therefore highly desirable to develop novel multi-functional systems that can exhibit antimicrobial properties for bone repair. Lanthanide glasses (Ln) and Graphene Oxide (GO) have shown very interesting properties, the first being used in sensing and imaging as well as enabling cell attachment and isomorphic replacements for calcium, the second being an antimicrobial. NOVA will develop a multifunctional composite system combining the useful properties of a lanthanide host glass with the antimicrobial activity of Graphene Oxide and the bioactivity of Hydroxyapatite (HA). The proposed research is a novel research direction, and there is no previously published research on what is proposed to be a new class of multi-functional composites.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-EF-ST - Standard EF

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2016

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Coordinator

THE UNIVERSITY OF BIRMINGHAM
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 195 454,80
Address
Edgbaston
B15 2TT Birmingham
United Kingdom

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Region
West Midlands (England) West Midlands Birmingham
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 195 454,80
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